CD274, Mouse IgG2a Fc Fusion Protein (CD274 Molecule, B7 Homolog 1, B7H1, B7-H1, B7-H, Programmed Cell Death 1 Ligand 1, PDCD1 Ligand 1, PDCD1L1, PDCD1LG1, Programmed Death Ligand 1, PDL1, PD-L1) (Biotin)[CD274 IgG2a Fc Fusion Protein]

  • Catalog number
    MBS635074
  • Price
    Please ask
  • Size
    NA
  • Products_type
    Protein
  • Properties
    Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
  • Conjugation
    Biotinylated
  • Description
    For cells, cell lines and tissues in culture till half confluency. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
  • Gene symbol
    CD274, HHLA2, RNY4P2, LRRC23, PDCD1LG2, PCDHGB7, NCR3LG1, CD86, TLX1NB, VSIR
  • Short name
    CD274, Mouse IgG2a Fc Protein (CD274 Molecule, B7 Homolog 1, B7H1, B7-H1, B7-H, Programmed Death 1 Ligand 1, PDCD1 Ligand 1, PDCD1L1, PDCD1LG1, Programmed Death Ligand 1, PDL1, PD-L1) ( )[CD274 IgG2a Fc Protein]
  • Technique
    Mouse, FC, mouses
  • Host
    mouse
  • Isotype
    IgG2a
  • Label
    Biotin
  • Species
    Mouse, Mouses
  • Alternative name
    CD274 molecule, Mouse IgG2a fragment c Fusion Protein (CD274 molecule Molecule, B7 Homolog 1, B7H1, B7-H1, B7-H, Programmed cellular Death 1 Ligand 1, programmed cellular death 1 Ligand 1, PDCD1L1, PDCD1LG1, Programmed Death Ligand 1, PDL1, PD-L1) (biotinilated)[CD274 molecule IgG2a fragment c Fusion Protein]
  • Alternative technique
    murine
  • Alternative to gene target
    CD274 molecule, CD274 and IDBG-47487 and ENSG00000120217 and 29126, protein binding, Cell surfaces, Cd274 and IDBG-157249 and ENSMUSG00000016496 and 60533, PD-L1 and IDBG-631351 and ENSBTAG00000000095 and 533834
  • Tissue
    cell
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    RNY4 pseudogene 2
  • Synonyms gene name
    • RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
    • RNA, Ro-associated Y4 pseudogene 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-08-25
  • Entrez gene record
  • RefSeq identity
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
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