PBX3 Antibody
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Catalog numberbs-12295R
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PricePlease ask
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Size0.1ml
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Long namePBX3 Primary Polyclonal Antibody
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Also known asPBX3 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPBX3
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SpecificityThis is a highly specific antibody against PBX3.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBX3
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Gene ID number5090
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenPbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesHomeobox protein PBX3; MGC134053; OTTHUMP00000064213; Pbx 3; Pbx3; PBX3_HUMAN; Pre B cell leukemia homeobox 3; Pre B cell leukemia transcription factor 3; Pre-B-cell leukemia transcription factor 3; RP11 336P12.1.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPBX3, PBX3-DT
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Short nameAnti-PBX3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePBX3 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetpre-B-cell leukemia homeobox 3, PBX3 and IDBG-85327 and ENSG00000167081 and 5090, sequence-specific DNA binding, nuclei, Pbx3 and IDBG-162874 and ENSMUSG00000038718 and 18516, BT.74403 and IDBG-638772 and ENSBTAG00000013314 and 539222
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Gene info
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Identity
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Gene
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Long gene namePBX homeobox 3
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Synonyms gene name
- pre-B-cell leukemia transcription factor 3
- pre-B-cell leukemia homeobox 3
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Locus
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Discovery year1990-09-10
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Entrez gene record
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Pubmed identfication
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Classification
- TALE class homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePBX3 divergent transcript
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Locus
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Discovery year2021-07-28
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Entrez gene record
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RefSeq identity
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Classification
- Divergent transcripts
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data