PBX3 Antibody

  • Catalog number
    bs-12295R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    PBX3 Primary Polyclonal Antibody
  • Also known as
    PBX3 PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    PBX3
  • Specificity
    This is a highly specific antibody against PBX3.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBX3
  • Gene ID number
    5090
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    Homeobox protein PBX3; MGC134053; OTTHUMP00000064213; Pbx 3; Pbx3; PBX3_HUMAN; Pre B cell leukemia homeobox 3; Pre B cell leukemia transcription factor 3; Pre-B-cell leukemia transcription factor 3; RP11 336P12.1.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    PBX3  
  • Gene symbol
    PBX3, PBX3-DT
  • Short name
    Anti-PBX3
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    PBX3 Polyclonal Antibody
  • Alternative technique
    antibodies
  • Alternative to gene target
    pre-B-cell leukemia homeobox 3, PBX3 and IDBG-85327 and ENSG00000167081 and 5090, sequence-specific DNA binding, nuclei, Pbx3 and IDBG-162874 and ENSMUSG00000038718 and 18516, BT.74403 and IDBG-638772 and ENSBTAG00000013314 and 539222
Gene info
  • Identity
  • Gene
  • Long gene name
    PBX homeobox 3
  • Synonyms gene name
    • pre-B-cell leukemia transcription factor 3
    • pre-B-cell leukemia homeobox 3
  • Locus
  • Discovery year
    1990-09-10
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • TALE class homeoboxes and pseudogenes
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    PBX3 divergent transcript
  • Locus
  • Discovery year
    2021-07-28
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Divergent transcripts
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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