PATJ Antibody

• Catalog number
  bs-12142R
• Price
  Please ask
• Size
  0.1ml

• Long name
  PATJ Primary Polyclonal Antibody
• Also known as
  PATJ PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  PATJ
• Specificity
  This is a highly specific antibody against PATJ.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PATJ
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The membranes of myelinating Schwann cells are joined by tight, gap and adherens junctions, all of which are found in regions of noncompact myelin: the paranodal loops, incisures of Schmidt-Lanterman and mesaxons. Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes. Pals-associated tight junction protein (PATJ), the human homolog of Drosophila Discs Lost, is differentially localized in myelinating Schwann cells. PATJ associates with Claudin-1, CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), and Pals1 (a Lin-7 associated protein). The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Channel interacting PDZ domain protein; Cipp; FLJ26982; hINADL; Inactivation no after potential D like protein; INAD like; InaD like Drosophila; INAD like protein; INADL; INADL protein; PALS 1 associated tight junction protein; PALS1 associated tight junction protein; PATJ; PDZ domain protein; PDZ domain protein Drosophila inaD like; Post synaptic density 95 / discs large / zonula occludens 1 domain protein; Protein associated to tight junctions; INADL_HUMAN .
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PATJ  
• Gene symbol
  PATJ-DT, PATJ
• Short name
  Anti-PATJ
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  PATJ Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55256
• Gene
  PATJ-DT
• Long gene name
  PATJ divergent transcript
• Locus
  1p31.3
• Discovery year
  2020-09-25
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:28881
• Gene
  PATJ
• Long gene name
  PATJ crumbs cell polarity complex component
• Synonyms gene
  • INADL
• Synonyms gene name
  • InaD-like (Drosophila)
  • PATJ, crumbs cell polarity complex component
• Synonyms
  • Cipp
• Synonyms name
  • inactivation-no-afterpotential D-like
  • Pals1-associated tight junction
• GenBank acession
  • AB044807
• Locus
  1p31.3
• Discovery year
  2004-12-23
• Entrez gene record
  10207
• Pubmed identfication
  • 9280290
  • 11374908
• RefSeq identity
  • NM_170605
• Classification
  • PDZ domain containing
  • Crumbs complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000008560

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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