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Alternative name1
Anti-Rabbit Polyclonal (IgG) to Human CASP8 / Caspase 8
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Alternative name2
Rabbit PAb (IgG) to Human CASP8 / Caspase 8
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Alternative name3
Lapin Polyclonal (IgG) to Homo sapiens CASP8 / Caspase 8
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Alternative name4
CASP8 / Caspase 8
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Alternative name5
Anti-CASP8 / Caspase 8 Antibody IHC-plus; CASP8; ALPS2B; Apoptotic protease Mch-5; Apoptotic cysteine protease; Casp-8; Caspase-8; CAP4; Caspase 8; MACH; MCH5; MORT1-associated ced-3 homolog; ICE-like apoptotic protease 5; Pro Caspase 8; FADD-like ICE; FLICE; MACH-alpha-1/2/3 protein; Human CASP8; Caspase 8
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Other names
caspase-8 isoform C; Caspase-8; caspase-8; FADD-like ICE; MACH-alpha-1/2/3 protein; apoptotic protease Mch-5; MACH-beta-1/2/3/4 protein; apoptotic cysteine protease; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; FADD-homologous ICE/CED-3-like protease; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
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Gene name
CASP8
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Gene name synonims
N/A
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Other gene names
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; MCH5; CASP-8; FLICE; MACH
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Rabbit
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Species reactivity
Bovine, Human, Monkey, Mouse, Rat
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Specificity and cross reactivity
Detects the processed forms (42/44kD, 25kDA and 14kD) of caspase 8. It is the antibody of choice for Immunoprecipitation. Species cross-reactivity: Human, mouse, rat, bovine, monkey.
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Purification method
Protein A Purified
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Form Appearance
10 mM PBS, pH 7.4.
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Concentration
1 miligram per 1 mililiter
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Storage and shipping
Long term: Store productone at -20 degrees Celsius.; Short term: +Store productone at +4 degrees Celsius.. Avoid repeat freeze-thaw cycles.
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Tested for
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
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French translation
anticorps
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Gene target
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Gene symbol
CASP8
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Short name
PAb (IgG) CASP8 / Caspase 8 Antibody
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Technique
Antibody, IgG, antibodies against human proteins, antibodies for, IgGs
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Isotype
IgG, IgG
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Species
Human, Humans
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Alternative name
polyclonal (Immunoglobulin G) to H. sapiens caspase 8, apoptosis-related cysteine peptidase / caspase 8 (antibody to-)
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Alternative technique
antibodies, immunoglobulins
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Alternative to gene target
caspase 8, apoptosis-related cysteine peptidase, ALPS2B and CAP4 and Casp-8 and FLICE and MACH and MCH5, CASP8 and IDBG-78534 and ENSG00000064012 and 841, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, nuclei, Casp8 and IDBG-157464 and ENSMUSG00000026029 and 12370, CASP8 and IDBG-643207 and ENSBTAG00000015718 and 507481
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