RELA Antibody

• Catalog number
  F47586-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  RELA
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IF, ELISA
• Recommended dilutions
  Immunofluorescence: 1:10-1:50,Western blot: 1:1000
• Notes
  Titration of the RELA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This RELA antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q04206
• Purity
  Antigen affinity
• Description
  NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivates NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs. [OMIM]
• Immunogen
  A portion of amino acids 166-195 from the human protein was used as the immunogen for this RELA antibody.
• Storage
  Aliquot the RELA antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RELA  
• Gene symbol
  RELA-DT, RELA
• Short name
  Anti-RELA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to RELA
• Alternative technique
  antibodies
• Alternative to gene target
  v-rel reticuloendotheliosis viral oncogene homolog A (avian), NFKB3 and p65, RELA and IDBG-57543 and ENSG00000173039 and 5970, ankyrin repeat binding, nuclei, Rela and IDBG-132298 and ENSMUSG00000024927 and 19697, BT.26220 and IDBG-644222 and ENSBTAG00000013895 and 508233

Gene info

• Identity
  HGNC:54185
• Gene
  RELA-DT
• Long gene name
  RELA divergent transcript
• Locus
  11q13.1
• Discovery year
  2019-02-21
• Entrez gene record
  105369347
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:9955
• Gene
  RELA
• Long gene name
  RELA proto-oncogene, NF-kB subunit
• Synonyms gene
  • NFKB3
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
  • v-rel avian reticuloendotheliosis viral oncogene homolog A
• Synonyms
  • p65
• GenBank acession
  • Z22951
• Locus
  11q13.1
• Discovery year
  1991-11-14
• Entrez gene record
  5970
• Pubmed identfication
  • 2001591
• RefSeq identity
  • NM_021975
• Classification
  • NF-kappa B complex subunits
  • IPT domain containing
• VEGA ID
  OTTHUMG00000166566

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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