OTUB1 Antibody

• Catalog number
  bs-11229R
• Price
  Please ask
• Size
  0.1ml

• Long name
  OTUB1 Primary Polyclonal Antibody
• Also known as
  OTUB1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  OTUB1
• Specificity
  This is a highly specific antibody against OTUB1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTUB1
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases. Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, thereby preventing protein degradation and playing an important role in protein turnover. OTUB1 interacts with GRAIL and, via this interaction, plays a role in the regulation and the induction of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens. Due to its interaction with GRAIL, OTUB1 is an important regulator of immune responses in secondary lymphoid organs.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Deubiquitinating enzyme OTUB1; hOTU1; OTB1; OTU domain containing ubiquitin aldehyde binding protein 1; OTU domain-containing ubiquitin aldehyde-binding protein 1; OTU1; Otub1; OTUB1_HUMAN; Otubain 1; Otubain-1; Ubiquitin specic processing protease OTUB1; Ubiquitin thioesterase OTUB1; Ubiquitin-specic-processing protease OTUB1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  OTUB1  
• Gene symbol
  OTUB1
• Short name
  Anti-OTUB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  OTUB1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23077
• Gene
  OTUB1
• Long gene name
  OTU deubiquitinase, ubiquitin aldehyde binding 1
• Synonyms gene name
  • OTU domain, ubiquitin aldehyde binding 1
• Synonyms
  • FLJ20113
  • FLJ40710
• GenBank acession
  • AY177200
• Locus
  11q13.1
• Discovery year
  2003-12-12
• Entrez gene record
  55611
• Pubmed identfication
  • 12704427
  • 19383985
• RefSeq identity
  • NM_017670
• Classification
  • OTU domain containing
• VEGA ID
  OTTHUMG00000167786

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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