Recombinant Oryzias latipes Leptin-B (LEP-B)

Products_type

Recombinant Protein
Products_short_name

[Leptin-B (LEP-B)]
Other_names

[leptin-B; Leptin-B; leptin-B]
Products_gene_name

[LEP-B]
Other_gene_names

[lep-b; LEP-B; ob-b]
Purity

>85% (SDS-PAGE)
Form

Lyophilized or liquid (Format to be determined during the manufacturing process)
Storage_stability

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Gene

Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Oryzias latipes Leptin-B LEP-B
Gene symbol

LEP, SNRPB, ORM2, ERAL1, OR1B1, SPIB, EXPH5, RELB, HLA-B, RPS6KA4
Short name

Recombinant Oryzias latipes Leptin-B (LEP-B)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E Coli or Yeast or Baculovirus or Mammalian Cell
Alternative name

Rec. Oryzias latipes Leptin-B (leptin-B)
Alternative technique

rec
Alternative to gene target

leptin, LEPD and OB and OBS, LEP and IDBG-39587 and ENSG00000174697 and 3952, peptide hormone receptor binding, Extracellular, Lep and IDBG-130781 and ENSMUSG00000059201 and 16846, OBESE and IDBG-635003 and ENSBTAG00000014911 and 280836

Identity

HGNC:6553
Gene

LEP
Long gene name

leptin
Synonyms gene
- OBS
- OB
Synonyms gene name
- leptin (murine obesity homolog)
- leptin (obesity homolog, mouse)
Locus

7q32.1
Discovery year

1993-01-26
Entrez gene record

3952
Pubmed identfication
- 1686014
- 16932309
Classification
- Neuropeptides
VEGA ID

OTTHUMG00000157564

Identity

HGNC:11153
Gene

SNRPB
Long gene name

small nuclear ribonucleoprotein polypeptides B and B1
Synonyms gene
- SNRPB1
Synonyms
- COD
- SmB/SmB'
- Sm-B/B'
- snRNP-B
Locus

20p13
Discovery year

1988-11-28
Entrez gene record

6628
Pubmed identfication
- 1376292
Classification
- Small nucleolar RNA protein coding host genes
- Sm spliceosomal proteins
VEGA ID

OTTHUMG00000031694

Identity

HGNC:3424
Gene

ERAL1
Long gene name

Era like 12S mitochondrial rRNA chaperone 1
Synonyms gene name
- Era (E. coli G-protein homolog)-like 1
- Era G-protein-like 1 (E. coli)
- Era-like 12S mitochondrial rRNA chaperone 1
Synonyms
- HERA-B
GenBank acession
- AF082657
Locus

17q11.2
Discovery year

1999-11-19
Entrez gene record

26284
Pubmed identfication
- 10945472
- 20604745
VEGA ID

OTTHUMG00000132675

Identity

HGNC:8181
Gene

OR1B1
Long gene name

olfactory receptor family 1 subfamily B member 1
Synonyms gene name
- olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
- olfactory receptor family 1 subfamily B member 1 (gene/pseudogene)
Synonyms
- OR9-B
GenBank acession
- AC006313
Locus

9q33.2
Discovery year

1999-12-09
Entrez gene record

347169
RefSeq identity
- NM_001004450
Classification
- Olfactory receptors, family 1
VEGA ID

OTTHUMG00000020616

Identity

HGNC:9956
Gene

RELB
Long gene name

RELB proto-oncogene, NF-kB subunit
Synonyms gene name
- v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Synonyms
- REL-B
GenBank acession
- M83221
Locus

19q13.32
Discovery year

1995-10-02
Entrez gene record

5971
Pubmed identfication
- 1531086
Classification
- IPT domain containing
- NF-kappa B complex subunits
VEGA ID

OTTHUMG00000162116

Identity

HGNC:4932
Gene

HLA-B
Long gene name

major histocompatibility complex, class I, B
Synonyms gene
- AS
Synonyms gene name
- ankylosing spondylitis
GenBank acession
- M15470
Locus

6p21.33
Discovery year

2001-06-22
Entrez gene record

3106
Pubmed identfication
- 3459708
RefSeq identity
- NM_005514
Classification
- C1-set domain containing
- Histocompatibility complex
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000031153
Locus Specific Databases
- IMGT/HLA Database

Identity

HGNC:10433
Gene

RPS6KA4
Long gene name

ribosomal protein S6 kinase A4
Synonyms gene name
- ribosomal protein S6 kinase, 90kD, polypeptide 4
Synonyms
- RSK-B
- MSK2
GenBank acession
- AJ010119
Locus

11q13.1
Discovery year

1999-03-10
Entrez gene record

8986
Pubmed identfication
- 9792677
- 9687510
RefSeq identity
- NM_003942
Classification
- AGC family kinases
- MicroRNA protein coding host genes
- MAPK activated protein kinases
VEGA ID

OTTHUMG00000046094

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data