ORC1L Antibody

• Catalog number
  bs-8998R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ORC1L Primary Polyclonal Antibody
• Also known as
  ORC1L PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ORC1L
• Specificity
  This is a highly specific antibody against ORC1L.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ORC1L/ORC1
• Gene ID number
  4998
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HSORC1; MmORC1; orc1; ORC1_HUMAN; ORC1L; Origin Recognition Complex 1; Origin recognition complex subunit 1 yeast homolog like; Origin recognition complex subunit 1; Origin recognition complex subunit 1 homolog; Origin recognition complex subunit 1 like S. cerevisia; Origin recognition complex subunit 1 like; Origin recognition complex subunit 1 S. cerevisiae homolog like; Origin recognition complex, subunit 1 like yeast; PARC1; Replication control protein 1.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ORC1L  
• Gene symbol
  ORC1
• Short name
  Anti-ORC1L
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ORC1L Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8487
• Gene
  ORC1
• Long gene name
  origin recognition complex subunit 1
• Synonyms gene
  • ORC1L
• Synonyms gene name
  • origin recognition complex, subunit 1 (yeast homolog)-like
  • origin recognition complex, subunit 1-like (yeast)
  • origin recognition complex, subunit 1 homolog (S. cerevisiae)
  • origin recognition complex, subunit 1
• Synonyms
  • HSORC1
  • PARC1
• Synonyms name
  • origin recognition complex, subunit 1, S. cerevisiae, homolog-like
  • origin recognition complex 1
  • replication control protein 1
• Locus
  1p32.3
• Discovery year
  1997-06-24
• Entrez gene record
  4998
• Pubmed identfication
  • 8884289
• RefSeq identity
  • NM_004153
• Classification
  • AAA ATPases
  • Origin recognition complex
• VEGA ID
  OTTHUMG00000008104

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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