O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate

Chemical available in other sizes

Please inquire size and price
Stock availability

Available in 2-3 weeks
Cas number

179344-98-0
Chemical s molecular weight

157.17
Chemical s main applications

V-PYRRO/NO is a metabolically activated nitric oxide (NO) donor drug that can be used to selectively target NO delivery to the liver. The compound is metabolized by the liver, and spontaneously decomposes with a half-life of 3 seconds, liberating NO. Infusion of 30nmol/kg of V-PYRRO/NO in rats causes only a slight drop in blood pressure. At concentrations >100ug, V-PYRRO/NO increases hepatocyte viability against TNF-a-induced apoptosis by approximately 2-fold compared to cells not treated with this compound. UV/Vis: lmax: 267nm e: 9,700
Chemical s category

Heterocycles, Nitric Oxide Reagents
Other name

1-(Ethenyloxy)-3-(2-pyrrolidinyl)-3-(5-pyrrolidinyl)-1-triazenamine 2-oxide; 1-[(Ethenyloxy)-NNO-azoxy]-pyrrolidine; V-PYRRO/NO;
Chemical s formula

C6H11N3O2
Physical properties

Pale Yellow Oil
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

Ethanol
Stability conditions

Store in Freezer (> 1 year at -20°)
Storage

No Data Available
Chemical s specifications

Gene target

O2-Vinyl Pyrrolidin-1-yl diazen-1-ium-1 2-diolate
Gene symbol

IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1, PIRC1
Short name

O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1 2-diolate
Alternative name

O2-Vinyl 1-(Pyrrolidin-1-yl)diazen-1-ium-1,2-diolate

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081