NR1H3 Antibody (LXR alpha)
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Catalog number
R30350
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Price
Please ask
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Size
0.1mg
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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
NR1H3 (LXR alpha)
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB
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Recommended dilutions
Western blot: 0.5-1ug/ml
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Notes
Titration of the NR1H3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This NR1H3 antibodyis to be used only for research purposes and not for diagnostics..
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Uniprot
Q13133
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Purity
Antigen affinity
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Description
LXR (Liver X Receptor) alpha, also known as NR1H3, is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, LXR activity is critical for physiologic lipid metabolism and transport.
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Immunogen
Amino acids 375-398 (QVERLQHTYVEALHAYVSINHPHD) were used as the immunogen for this NR1H3 antibody (100% homologous in human, mouse and rat).
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Storage
The lyophilized NR1H3 antibody can be stored at 4oC to -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. After reconstitution, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Additional description
The Anti-NR1H3 (LXR alpha) is a α- or alpha protein sometimes glycoprotein present in blood.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
NR1H3, NR1H2
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Short name
Anti-NR1H3 (LXR alpha)
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Rabbit IgG
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Alternative name
Antibodies to NR1H3 (LXR alpha)
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Alternative technique
antibodies
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Alternative to gene target
nuclear receptor subfamily 1, group H, member 3, LXR-a and LXRA and RLD-1, NR1H3 and IDBG-42877 and ENSG00000025434 and 10062, transcription regulatory region DNA binding, nuclei, Nr1h3 and IDBG-190792 and ENSMUSG00000002108 and 22259, NR1H3 and IDBG-637355 and ENSBTAG00000010681 and 507176
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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