R-PTP eta (T23-5E6) Monoclonal Antibody
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Catalog numberbsm-50423M
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PricePlease ask
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Size0.1ml
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Long nameR-PTP eta (T23-5E6) Monoclonal Antibody
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Also known asR-PTP eta (T23-5E6) Monoclonal Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenR-PTP eta
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SpecificityThis is a highly specific antibody against R-PTP eta.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityMonoclonal
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Clone numberT23-5E6
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SourceRecombinant human protein purified from E.coli
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Swiss ProtQ12913
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Tested ApplicationsWB
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Recommended dilutionsWB (1:2000)
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Cross reactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenReceptor-type tyrosine-protein phosphatase eta(Also known as DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA) is an enzyme that in humans is encoded by the PTPRJ gene.[1][2][3] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This PTP is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 (PLCG1) and Linker for Activation of T Cells (LAT). This PTP was also found to dephosphorylate PDGF beta receptor, and may be involved in UV-induced signal transduction.[3] PTPRJ has been shown to interact with CTNND1.[4]
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Purification methodAmmonium sulfate precipitation
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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French translationanticorps
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Gene target
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Gene symbolPTPRK, PTPN13, RRAS, PTPRO, PTPRR, DAD1P1, HNRNPR, CLDN4, MC1R, ACP1
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Short nameAnti-R-PTP eta
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TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
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HostMouse (Mus musculus)
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IsotypeImmunoglobulin G (IgG)2b
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Alternative nameR-PTP eta (T23-5E6) Monoclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type K
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-09
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
- Immunoglobulin like domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase non-receptor type 13
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Synonyms gene name
- protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
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Synonyms
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Synonyms name
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Locus
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Discovery year1995-02-17
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases non-receptor type
- PDZ domain containing
- FERM domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRAS related
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Synonyms gene name
- related RAS viral (r-ras) oncogene homolog
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type O
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-02-22
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Entrez gene record
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Pubmed identfication
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Classification
- Protein tyrosine phosphatases receptor type
- Fibronectin type III domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein tyrosine phosphatase receptor type R
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-10-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein tyrosine phosphatases receptor type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefender against cell death 1 pseudogene 1
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Synonyms gene
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Synonyms gene name
- defender against cell death 1-like
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Synonyms
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Locus
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Discovery year2007-07-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene nameheterogeneous nuclear ribonucleoprotein R
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-06-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heterogeneous nuclear ribonucleoproteins
- RNA binding motif containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclaudin 4
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Claudins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemelanocortin 1 receptor
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Synonyms gene name
- melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Melanocortin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameacid phosphatase 1
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Synonyms gene name
- acid phosphatase 1, soluble
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Acid phosphatases
- Class II Cys-based phosphatases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data