Noxa Antibody

• Catalog number
  bs-7074R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Noxa Primary Polyclonal Antibody
• Also known as
  Noxa PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Noxa
• Specificity
  This is a highly specific antibody against Noxa.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Noxa
• Gene ID number
  5366
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Adult T cell leukemia derived PMA responsive; APR; APR_HUMAN; Immediate early response protein APR; Immediate-early-response protein APR; Phorbol 12 myristate 13 acetate induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; PMA induced protein 1; PMA-induced protein 1; PMAIP1; Protein Noxa.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Noxa  
• Gene symbol
  PMAIP1
• Short name
  Anti-Noxa
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Noxa Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9108
• Gene
  PMAIP1
• Long gene name
  phorbol-12-myristate-13-acetate-induced protein 1
• Synonyms
  • APR
  • NOXA
• GenBank acession
  • D90070
• Locus
  18q21.32
• Discovery year
  1991-08-12
• Entrez gene record
  5366
• Pubmed identfication
  • 2398525
  • 12879012
• RefSeq identity
  • NM_021127
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000132765

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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