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Alternative name1
Anti-NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor)
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Alternative name2
NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor)
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Alternative name3
NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor)
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Alternative name4
NOT1
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Alternative name5
Anti -NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor)
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Other names
Not1, isoform F; N/A; CG34407 gene product from transcript CG34407-RC; Not1, isoform C; CG34407-PC; Not1-PC; Not1, isoform E; CG34407-PE; Not1-PE; Not1, isoform D; CG34407-PD; Not1-PD; Not1, isoform F; CG34407-PF; Not1-PF; N/A; N/A
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Gene name
N/A
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Gene name synonims
N/A
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Other gene names
Not1; N/A; anon-EST:Liang-1.29; anon-WO0118547.221; CG1874; CG1884; CG34407; clone 1.29; DmelCG34407; NOT; not1; NOT1; N/A
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Category
Antibodies
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Clonality
Polyclonal
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Immunoglobulin isotype
IgG
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Clone
Polyclonal antibody
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Host organism
Host: Rabbit; Source: Human
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Species reactivity
Human, Rodent
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Specificity and cross reactivity
Recognizes Nurr1/NOT1 (Cys4 zinc finger of nuclear receptor type family), a zinc finger transcription factor. Species Reactivity: Human and rodent.
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Purification method
Affinity Purified by affinity chromatography.
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Form Appearance
Supplied as a liquid in PBS pH 7.2, 40% glycerol. No preservative added.
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Concentration
N/A
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Storage and shipping
Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze productone should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested for
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
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Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Properties
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Additional description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Finger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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French translation
anticorps
