NKH 477

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Cas number

138605-00-2
Chemical s molecular weight

546.09
Chemical s main applications

NKH 477 is a water-soluble analog of Forskolin (F701800), that is a potent activator of adenylyl cyclase, which shows some selectivity for cardiac (type V) adenylyl cyclase).
Other name

N,N-Dimethyl-β-alanine (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester Hydrochloride; N,N-Dimethyl-β-alanine [3R-(3α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl Ester Hydrochloride; 1H-Naphtho[2,1-b]pyran, β-alanine deriv.; 6-(3-Dimethylaminopropionyl)forskolin Hydrochloride; Adehl; Colforsin Dapropate Hydrochloride
Chemical s formula

C27H44ClNO8
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Identity

HGNC:4313
Gene

GLDC
Long gene name

glycine decarboxylase
Synonyms gene name
- glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P)
- glycine dehydrogenase (decarboxylating)
Synonyms
- GCSP
- NKH
Synonyms name
GenBank acession
- D90239
Locus

9p24.1
Discovery year

1992-04-08
Entrez gene record

2731
Pubmed identfication
- 1993704
- 1996985
RefSeq identity
- NM_000170
VEGA ID

OTTHUMG00000019524
Locus Specific Databases
- LRG_643