Nilotinib for cell activation

Nilotinib for cell activation is available 0 time from Biovision labs

  • Description
    A potent, selective BCR-ABL inhibitor that fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib (Cat. No. 1625-100, 1000).  Nilotinib is not only more potent than imatinib against wild-type BCR-ABL (IC₅₀ < 30 nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants. 
  • Peptide sequence
    N/A
  • CAS number
    641571-10-0
  • Molecular weight
    529.52
  • Category
    Biochemicals
  • Molecular formula
    C₂₈H₂₂F₃N₇O
  • Physical appearance
    Off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (50 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    24 months
  • Storage instructions
    Protect from air and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Nilotinib for activation
  • Technique
    activation
  • Alternative name
    Nilotinib to measure cellular activation
  • Tissue
    cell
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