Nibrin (Nijmegen Breakage Syndrome, NBS1)

Products_type

Antibody
Products_short_name

[Nibrin]
Products_name_syn

[Anti -Nibrin (Nijmegen Breakage Syndrome, NBS1)]
Other_names

[nibrin; Nibrin; nibrin; OTTHUMP00000204086; OTTHUMP00000204088; cell cycle regulatory protein p95; Nijmegen breakage syndrome 1 (nibrin); p95 protein of the MRE11/RAD50 complex; nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1]
Other_gene_names

[NBN; NBN; ATV; NBS; P95; NBS1; AT-V1; AT-V2; FLJ10155; MGC87362; NBS; NBS1; P95]
Clonality

Monoclonal
Clone

[3J15]
Reactivity

Human
Specificity

Recognizes human NibrinRecognizes Nibrin/Nbs1, Mr 95kD. A non-specific protein was also detected at Mr 33kD in some lysates, but not Jurkat cell lysate. Species Crossreactivity: Human, NOT mouse.
Purity

Affinity Purified Purified by Protein G affinity chromatography.
Form

Supplied as a liquid in 100mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide before the addition of glycerol to 30%.
Storage_stability

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

Western Blot (WB), Immunoprecipitation (IP)

Identity

HGNC:22948
Gene

NLRP2
Long gene name

NLR family pyrin domain containing 2
Synonyms gene
- NALP2
Synonyms gene name
- NACHT, leucine rich repeat and PYD containing 2
Synonyms
- FLJ20510
- PYPAF2
- NBS1
- PAN1
- CLR19.9
Synonyms name
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
GenBank acession
- AK000517
Locus

19q13.42
Discovery year

2003-10-28
Entrez gene record

55655
Pubmed identfication
- 12563287
- 11270363
RefSeq identity
- NM_017852
Classification
- Pyrin domain containing
- NLR family
VEGA ID

OTTHUMG00000167763