NFKB3, phosphorylated (Ser529) (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor Of kappa Light Polypeptide Gene Enhancer In B-cells 3, RELA)

  • Catalog number
    MBS645771
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [NFKB3]
  • Products_name_syn
    [Anti -NFKB3, phosphorylated (Ser529) (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 Subunit, Nuclear Factor Of kappa Light Polypeptide Gene Enhancer In B-cells 3, RELA)]
  • Clonality
    Polyclonal
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes detects endogenous levels of human NFKB3 only when phosphorylated at serine 529. Species Crossreactivity: Mouse and rat.
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography.
  • Form
    Supplied as a liquid in PBS, pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    Western Blot (WB), Immunohistochemistry (IHC)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Gene target
    NFKB3   phosphorylated   Ser529   Transcription   Factor   p65   Factor   NF-kappa-B   p65   Subunit   Factor   kappa   Light   Polypeptide   Gene   Enhancer   B-cells   RELA  
  • Gene symbol
    RELA, NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFATC2, NFYC
  • Short name
    NFKB3, phosphorylated (Ser529) (Transcription Factor p65, Factor NF-kappa-B p65 Subunit, Factor Of kappa Light Polypeptide Enhancer In B-cells 3, RELA)
  • Technique
    light
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    NFKB3, phosphorylated (Ser529) (Transcription Factor p65, Nuclear Factor NF-kappa-B p65 functionnal sequence, Nuclear Factor on kappa Light multipeptide Gene Enhancer In B-cells 3, v-v-rel reticuloendotheliosis viral oncogene homolog (avian) reticuloendotheliosis viral oncogene homolog A (avian))
  • Alternative to gene target
    v-rel reticuloendotheliosis viral oncogene homolog A (avian), NFKB3 and p65, RELA and IDBG-57543 and ENSG00000173039 and 5970, ankyrin repeat binding, nuclei, Rela and IDBG-132298 and ENSMUSG00000024927 and 19697, BT.26220 and IDBG-644222 and ENSBTAG00000013895 and 508233
  • Tissue
    cells
Gene info
  • Identity
    HGNC:9955
  • Gene
    RELA
  • Long gene name
    RELA proto-oncogene, NF-kB subunit
  • Synonyms gene
  • Synonyms gene name
    • nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
    • v-rel avian reticuloendotheliosis viral oncogene homolog A
  • Synonyms
  • GenBank acession
  • Locus
    11q13.1
  • Discovery year
    1991-11-14
  • Entrez gene record
    5970
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • NF-kappa B complex subunits
    • IPT domain containing
  • VEGA ID
    OTTHUMG00000166566
Gene info
Gene info
  • Identity
    HGNC:7780
  • Gene
    NFE2
  • Long gene name
    nuclear factor, erythroid 2
  • Synonyms gene name
    • nuclear factor (erythroid-derived 2), 45kD
    • nuclear factor (erythroid-derived 2), 45kDa
  • Synonyms
  • GenBank acession
  • Locus
    12q13.13
  • Discovery year
    1993-11-03
  • Entrez gene record
    4778
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
    OTTHUMG00000169761
Gene info
Gene info
Gene info
  • Identity
    HGNC:6057
  • Gene
    INA
  • Long gene name
    internexin neuronal intermediate filament protein alpha
  • Synonyms gene
  • Synonyms gene name
    • internexin neuronal intermediate filament protein, alpha
  • Synonyms
  • GenBank acession
  • Locus
    10q24.33
  • Discovery year
    1999-03-24
  • Entrez gene record
    9118
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Intermediate filaments Type IV
  • VEGA ID
    OTTHUMG00000018986
Gene info
Gene info
  • Identity
    HGNC:7775
  • Gene
    NFATC1
  • Long gene name
    nuclear factor of activated T cells 1
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
    • nuclear factor of activated T-cells 1
  • Synonyms
  • GenBank acession
  • Locus
    18q23
  • Discovery year
    1994-11-16
  • Entrez gene record
    4772
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nuclear factors of activated T-cells
    • IPT domain containing
  • VEGA ID
    OTTHUMG00000132897
Gene info
  • Identity
    HGNC:7776
  • Gene
    NFATC2
  • Long gene name
    nuclear factor of activated T cells 2
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    • nuclear factor of activated T-cells 2
  • Synonyms
  • GenBank acession
  • Locus
    20q13.2
  • Discovery year
    1994-11-16
  • Entrez gene record
    4773
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • IPT domain containing
    • Nuclear factors of activated T-cells
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000032747
Gene info
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