Factor X Antibody, ALEXA FLUOR 594

• Catalog number
  bs-9501R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  Factor X Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-Factor X PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Factor X
• Specificity
  This is a highly specific antibody against Factor X.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Activated factor Xa heavy chain
• Gene ID Number
  2159
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor X (Stuart Prower factor, FX, F10) is a vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. The mature form of Factor X (Factor X A) is generated by Factor IX A- or Factor VII A-mediated cleavage at the tripeptide sequence, Arg-Lys-Arg, to yield a disulfide linked dimer. Together with the cofactor Factor V A and Ca2+ on the surface of platelets or endothelial cells, Factor X A coordinates as part of the prothrombinase complex, which mediates proteolysis of Prothrombin into active Thrombin. Mutations at the Factor X locus resulting in Factor X deficiencies can contribute to hemorrhagic diathesis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  Activated factor Xa heavy chain; Coagulation factor; Coagulation factor X; EC 3.4.21.6; F10 antibody FA10_HUMAN; Factor Xa; FX; FXA; OTTHUMP00000018735; Prothrombinase; Stuart factor; Stuart Prower factor; Stuart-Prower factor; Coagulation factor X; Factor X heavy chain.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  Factor  
• Gene symbol
  RFXAP, RFX7, NFIX
• Short name
  Anti-Factor X
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Factor X Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9988
• Gene
  RFXAP
• Long gene name
  regulatory factor X associated protein
• Synonyms gene name
  • regulatory factor X-associated protein
• GenBank acession
  • Y12812
• Locus
  13q13.3
• Discovery year
  1997-11-05
• Entrez gene record
  5994
• Pubmed identfication
  • 9118943
• RefSeq identity
  • NM_000538
• VEGA ID
  OTTHUMG00000016738
• Locus Specific Databases
  • RFXAPbase: Mutation registry for Regulatory factor X-associated protein deficiency
  • LRG_103

Gene info

• Identity
  HGNC:25777
• Gene
  RFX7
• Long gene name
  regulatory factor X7
• Synonyms gene
  • RFXDC2
• Synonyms gene name
  • regulatory factor X domain containing 2
  • regulatory factor X, 7
• Synonyms
  • FLJ12994
• Locus
  15q21.3
• Discovery year
  2005-07-25
• Entrez gene record
  64864
• RefSeq identity
  • NM_022841
• Classification
  • Regulatory factor X family
• VEGA ID
  OTTHUMG00000172508

Gene info

• Identity
  HGNC:7788
• Gene
  NFIX
• Long gene name
  nuclear factor I X
• Synonyms gene name
  • nuclear factor I/X (CCAAT-binding transcription factor)
• Synonyms
  • NF1A
• Synonyms name
  • CCAAT-binding transcription factor
• GenBank acession
  • U18761
• Locus
  19p13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4784
• Pubmed identfication
  • 8340106
  • 7590749
• RefSeq identity
  • NM_002501
• Classification
  • Nuclear factor I family
• VEGA ID
  OTTHUMG00000180726

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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