Mouse anti NCAM / CD56

  • Catalog number
    MBS570110
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [NCAM / CD56]
  • Clonality
    Monoclonal
  • Clone
    [123C3]
  • Reactivity
    Human, Zebrafish
  • Specificity
    123C3 was defined as a cluster I antibody during the First International Workshop on Small Cell Lung Cancer (SCLC) Antibodies. 123C3 recognizes an epitope in the NCAM exons 11-13 which is dependent on an intact conformation of the first fibronectin type-III homologous domain encoded by these exons. 123C3 stains NCAM which is present in small cell lung cancer and lung carcinoids. It also reacts with a number of non-small cell lung carcinomas and neuroendocrine and neuronal derived tissues. In addition, 123C3 is internalized after binding to its antigen on SCLC cell lines, making it an excellent reagent for tumor imaging in xenograft models.
  • Form
    Each vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
  • Storage_stability
    Store at 4 degree C, or in small aliquots at -20 degree C.
  • Tested_application
    Immunocytochemistry (IHC), Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB)
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
    NCAM   CD56  
  • Gene symbol
    NCAM1, L1CAM
  • Short name
    Mouse anti NCAM / CD56
  • Technique
    Mouse, anti, antibody to, mouses
  • Host
    Mouse
  • Isotype
    IgG1
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse antibody to NCAM / CD56
  • Alternative technique
    murine, antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    neural cell adhesion molecule 1
  • Synonyms
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Fibronectin type III domain containing
    • CD molecules
    • Ig-like cell adhesion molecule family
    • I-set domain containing
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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