Nanaomycin A

• Catalog number
  2790-1
• Price
  Please ask
• Size
  1 mg

• Alternative_name
  2-[(1S, 3R)-9-hydroxy-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-3-yl]acetic acid; Nanafrocin, Nanafrocine, Nanafrocinum, Rosanomycin A
• Description
  Nanaomycin A is a selective DNA methyltransferase 3B (DNMT3B) inhibitor. It induces antiproliferative effects in three different tumor cell lines originating from different tissues. Nanaomycin A treatment reduces the global methylation levels in all three cell lines and reactivates transcription of the RASSF1A tumor suppressor gene.
• CAS Number
  52934-83-5
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₄O₆
• Molecular Weight
  302.28
• Cell Permeable
  Y
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective DNA methyltransferase 3B (DNMT3B) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  40586
• PubChem CID Link
  ttps://pubchem.ncbi.nlm.nih.gov/compound/40586?from=summary
• SMILES
  CC1C2=C(CC(O1)CC(=O)O)C(=O)C3=C(C2=O)C(=CC=C3)O
• InChi
  InChI=1S/C16H14O6/c1-7-13-10(5-8(22-7)6-12(18)19)15(20)9-3-2-4-11(17)14(9)16(13)21/h2-4,7-8,17H,5-6H2,1H3,(H,18,19)
• InChi Key
  ZCJHPTKRISJQTN-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Nanaomycin  
• Short name
  Nanaomycin A
• Alternative name
  Nanaomycin A

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