N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester

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Stock availability

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Cas number

73058-37-4
Chemical s molecular weight

285.3
Chemical s main applications

Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates.
Chemical s category

Amino Acids & Derivatives, Aromatics
Other name

N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester; 3-Phenyl-2-[(pyrazine-2-carbonyl)amino]propionic Acid Methyl Ester;
Chemical s formula

C15H15N3O3
Physical properties

Yellow Oil
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

Chloroform, Dichloromethane, Dimethyl Sulfoxide, Ethanol,
Stability conditions

No Data Available
Storage

-20°C Freezer
Chemical s specifications
Description

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,

Gene target

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
Gene symbol

CPT1A, POM121L2, L3MBTL2, CLDN10, RPL32P1, FABP1, COX7A2, NFIA, ATRN, ANP32E
Short name

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
Alternative name

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester

Identity

HGNC:13973
Gene

POM121L2
Long gene name

POM121 transmembrane nucleoporin like 2
Synonyms gene name
- POM121 membrane glycoprotein-like 2 (rat)
- POM121 membrane glycoprotein-like 2
- POM121 transmembrane nucleoporin-like 2
Synonyms
- POM121-L
GenBank acession
- AL021808
Locus

6p22.1
Discovery year

2001-07-20
Entrez gene record

94026
RefSeq identity
- NM_033482
VEGA ID

OTTHUMG00000014475

Identity

HGNC:18594
Gene

L3MBTL2
Long gene name

L3MBTL histone methyl-lysine binding protein 2
Synonyms gene name
- l(3)mbt-like 2 (Drosophila)
- L3MBTL2, polycomb repressive complex 1 subunit
Synonyms
GenBank acession
- AJ305226
Locus

22q13.2
Discovery year

2002-04-29
Entrez gene record

83746
Pubmed identfication
- 11682070
- 21596310
RefSeq identity
- NM_031488
Classification
- MBT domain containing
VEGA ID

OTTHUMG00000150942

Identity

HGNC:16673
Gene

ANP32E
Long gene name

acidic nuclear phosphoprotein 32 family member E
Synonyms gene name
- acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
Synonyms
- LANPL
- MGC5350
- LANP-L
GenBank acession
- AK092672
Locus

1q21.2
Discovery year

2003-04-15
Entrez gene record

81611
Pubmed identfication
- 12438741
RefSeq identity
- NM_030920
Classification
- ANP32 acidic nuclear phosphoproteins
VEGA ID

OTTHUMG00000012547