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Also known as
Muscarinic Receptor M4
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Other names
muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M4; muscarinic acetylcholine receptor M4; OTTHUMP00000205575; cholinergic receptor, muscarinic 4; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CHRM4; CHRM4; HM4; M4R; N/A
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Gene name synonims
CHRM4; CHRM4; HM4; M4R; N/A
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Other gene names
CHRM4; CHRM4; HM4; M4R; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
2Q146
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes M4 muscarinic acetylcholine receptor. It is not reactive with the other subtypes. Species Crossreactivity: rat, mouse and monkey. Reacts weakly with human by Western Blot.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Purified
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Form Appearance
Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
