Munc13 Antibody

• Catalog number
  bs-11353R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Munc13 Primary Polyclonal Antibody
• Also known as
  Munc13 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Munc13
• Specificity
  This is a highly specific antibody against Munc13.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Munc13
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Munc 13s are homologues of the C. elegans unc-13 gene product. Three brain specific isoforms are expressed in rat: Munc 13-1, -13-2, and -13-3. Munc 13-1 is a peripheral membrane protein that is enriched in synaptosomes and localized to plasma membranes but absent from synaptic vesicles. It has multiple regulatory domains (C1 and C2 domains) that may mediate diacylglycerol, phospholipid, and calcium binding. The C terminus of Munc 13-1 interacts directly with a putative coiled coil domain in the N-terminal part of syntaxin. It has been shown that Munc 13 is involved in priming synaptic vesicles. These activated vesicles can be released immediately on Ca2+ influx.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Munc 13; KIAA1032; Munc13-1; Protein unc-13 homolog A; UN13A; Unc 13 homolog A; Unc13a; UNC13A; Unc13h1; UN13A_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Munc13  
• Gene symbol
  UNC13D, UNC13A, UNC13C
• Short name
  Anti-Munc13
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Munc13 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23147
• Gene
  UNC13D
• Long gene name
  unc-13 homolog D
• Synonyms gene name
  • unc-13 homolog D (C. elegans)
• Synonyms
  • Munc13-4
• GenBank acession
  • AK024474
• Locus
  17q25.3
• Discovery year
  2003-10-16
• Entrez gene record
  201294
• RefSeq identity
  • NM_199242
• Classification
  • UNC13 homologs
• VEGA ID
  OTTHUMG00000179895
• Locus Specific Databases
  • UNC13Dbase: Mutation registry for Familial hemophagocytic lymphohistiocytosis 3
  • CCHMC-BMI & UC Hearing Loss Mutation Database
  • LRG_122

Gene info

• Identity
  HGNC:23150
• Gene
  UNC13A
• Long gene name
  unc-13 homolog A
• Synonyms gene name
  • unc-13 homolog A (C. elegans)
• Synonyms
  • KIAA1032
  • Munc13-1
• GenBank acession
  • AB028955
• Locus
  19p13.11
• Discovery year
  2003-10-16
• Entrez gene record
  23025
• RefSeq identity
  • NM_001080421
• Classification
  • UNC13 homologs
• VEGA ID
  OTTHUMG00000163877

Gene info

• Identity
  HGNC:23149
• Gene
  UNC13C
• Long gene name
  unc-13 homolog C
• Synonyms gene name
  • unc-13 homolog C (C. elegans)
• Synonyms
  • Munc13-3
  • DKFZp547H074
• GenBank acession
  • AK091491
• Locus
  15q21.3
• Discovery year
  2003-10-16
• Entrez gene record
  440279
• RefSeq identity
  • NM_173166
• Classification
  • UNC13 homologs
• VEGA ID
  OTTHUMG00000172542

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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