MUC18/ CD146 Antibody
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Catalog numberGEN438396
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PricePlease ask
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Size100ug
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Also known asMUC18
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Other namesN/A; Cell surface glycoprotein MUC18; cell surface glycoprotein MUC18; Gicerin; melanoma adhesion molecule; cell surface glycoprotein P1H12; melanoma-associated antigen A32; melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; melanoma cell adhesion molecule; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD_antigen: CD146
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameMCAM
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Gene name synonimsN/A
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Other gene namesMCAM; MCAM; CD146; MUC18; MUC18
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1, kappa
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CloneOJ79c
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityThe human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceN/A
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ConcentrationN/A
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Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applicationsELISA (For coating, order antibody without BSA), Flow Cytometry (0.5-1ug/million cells), Immunofluorescence (0.5-1.0ug/ml), Immunoprecipitation (1-2ug/500ug protein), Western Blot (0.5-1.0ug/ml), Immunohistology (Frozen) (0.5-1.0ug/ml for 30 min at RT Opt
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMCAM
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Short nameMUC18/ CD146 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-MUC18/ CD146
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namemelanoma cell adhesion molecule
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-12-18
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Entrez gene record
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Pubmed identfication
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Classification
- Ig-like cell adhesion molecule family
- C2-set domain containing
- V-set domain containing
- MicroRNA protein coding host genes
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data