mTOR, PI3K/PI4K (mTAb1, Mammalian Target of Rapamycin, FRAP, RAFT) Antibody

• Catalog number
  GEN600933
• Price
  Please ask
• Size
  100ul

• Also known as
  mTOR, PI3K/PI4K
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  6k277
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human mTOR/FRAP. Species Crossreactivity: Mouse and rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Supernatant
• Form Appearance
  Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  mTOR   PI3K/PI4K   mTAb1   Mammalian   Rapamycin   FRAP   RAFT  
• Gene symbol
  PIK3C2B, PIK3CA, PIK3C2A, PIK3R5, PI4KB, PI4KA, MTOR
• Short name
  mTOR, PI3K/PI4K (mTAb1, Mammalian of Rapamycin, FRAP, RAFT) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-mTOR, PI3K/PI4K (mTAb1, Mammalian Target of Rapamycin, FRAP, RAFT)
• Alternative technique
  antibodies
• Alternative to gene target
  mechanistic target of rapamycin (serine/threonine kinase), FRAP and FRAP1 and FRAP2 and RAFT1 and RAPT1, MTOR and IDBG-89258 and ENSG00000198793 and 2475, transferase activity, nuclei, Mtor and IDBG-204403 and ENSMUSG00000028991 and 56717, MTOR and IDBG-632731 and ENSBTAG00000015325 and 100139219

Gene info

• Identity
  HGNC:8972
• Gene
  PIK3C2B
• Long gene name
  phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
• Synonyms gene name
  • phosphoinositide-3-kinase, class 2, beta polypeptide
  • phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
• Synonyms
  • C2-PI3K
  • PI3K-C2beta
• GenBank acession
  • Y11312
• Locus
  1q32.1
• Discovery year
  1998-05-21
• Entrez gene record
  5287
• Pubmed identfication
  • 9144573
  • 9830063
• RefSeq identity
  • NM_002646
• Classification
  • Phosphatidylinositol 3-kinase subunits
• VEGA ID
  OTTHUMG00000036101

Gene info

• Identity
  HGNC:8975
• Gene
  PIK3CA
• Long gene name
  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
• Synonyms gene name
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
• Synonyms
  • PI3K
• Locus
  3q26.32
• Discovery year
  1994-07-15
• Entrez gene record
  5290
• Pubmed identfication
  • 1322797
• Classification
  • Phosphatidylinositol 3-kinase subunits
• VEGA ID
  OTTHUMG00000157311
• Locus Specific Databases
  • LRG_310

Gene info

• Identity
  HGNC:8971
• Gene
  PIK3C2A
• Long gene name
  phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
• Synonyms gene name
  • phosphoinositide-3-kinase, class 2, alpha polypeptide
  • phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
• Synonyms
  • PI3K-C2alpha
• GenBank acession
  • Y13367
• Locus
  11p15.1
• Discovery year
  1998-05-21
• Entrez gene record
  5286
• Pubmed identfication
  • 9337861
• RefSeq identity
  • NM_002645
• Classification
  • Phosphatidylinositol 3-kinase subunits
• VEGA ID
  OTTHUMG00000166036

Gene info

• Identity
  HGNC:30035
• Gene
  PIK3R5
• Long gene name
  phosphoinositide-3-kinase regulatory subunit 5
• Synonyms gene name
  • phosphoinositide-3-kinase, regulatory subunit 5
• Synonyms
  • P101-PI3K
  • p101
• GenBank acession
  • AF128881
• Locus
  17p13.1
• Discovery year
  2004-10-13
• Entrez gene record
  23533
• Pubmed identfication
  • 12507995
• RefSeq identity
  • NM_014308
• VEGA ID
  OTTHUMG00000108197

Gene info

• Identity
  HGNC:8984
• Gene
  PI4KB
• Long gene name
  phosphatidylinositol 4-kinase beta
• Synonyms gene
  • PIK4CB
• Synonyms gene name
  • phosphatidylinositol 4-kinase, catalytic, beta
• Synonyms
  • PI4K-BETA
  • pi4K92
• GenBank acession
  • AB005910
• Locus
  1q21.3
• Discovery year
  1998-04-07
• Entrez gene record
  5298
• Pubmed identfication
  • 9020160
  • 9405938
• RefSeq identity
  • NM_002651
• VEGA ID
  OTTHUMG00000012348

Gene info

• Identity
  HGNC:8983
• Gene
  PI4KA
• Long gene name
  phosphatidylinositol 4-kinase alpha
• Synonyms gene
  • PIK4CA
• Synonyms gene name
  • phosphatidylinositol 4-kinase, catalytic, alpha
• Synonyms
  • PI4K-ALPHA
  • pi4K230
• Synonyms name
  • phosphatidylinositol 4-kinase IIIα
  • phosphatidylinositol 4-kinase III alpha
• GenBank acession
  • L36151
• Locus
  22q11.21
• Discovery year
  1998-04-07
• Entrez gene record
  5297
• Pubmed identfication
  • 7961848
  • 8662589
  • 29229838
• RefSeq identity
  • NM_058004
• Classification
  • PI4KA lipid kinase complex
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000167440

Gene info

• Identity
  HGNC:3942
• Gene
  MTOR
• Long gene name
  mechanistic target of rapamycin kinase
• Synonyms gene
  • FRAP
  • FRAP2
  • FRAP1
• Synonyms gene name
  • FK506 binding protein 12-rapamycin associated protein 1
  • mechanistic target of rapamycin (serine/threonine kinase)
  • mechanistic target of rapamycin
• Synonyms
  • RAFT1
  • RAPT1
  • FLJ44809
• Synonyms name
  • FK506 binding protein 12-rapamycin associated protein 2
  • rapamycin target protein
  • FKBP12-rapamycin complex-associated protein 1
  • FKBP-rapamycin associated protein
  • rapamycin associated protein FRAP2
  • dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1)
  • rapamycin and FKBP12 target 1
  • mammalian target of rapamycin
• GenBank acession
  • L34075
• Locus
  1p36.22
• Discovery year
  1995-07-18
• Entrez gene record
  2475
• Pubmed identfication
  • 8008069
  • 8660990
• RefSeq identity
  • NM_004958
• Classification
  • MTOR complex 1
  • MTOR complex 2
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000002001
• Locus Specific Databases
  • LRG_734

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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