SMYD2 Antibody
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Catalog numberbs-16796R
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PricePlease ask
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Size0.1ml
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Long nameSMYD2 Primary Polyclonal Antibody
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Also known asSMYD2 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenSMYD2
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SpecificityThis is a highly specific antibody against SMYD2.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range290-433/433
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Subcellular locationCytoplasm, Nucleus
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMYD2
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Gene ID number56950
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Swiss ProtQ9NRG4
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Tested ApplicationsIHC-P, IF(IHC-P)
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Recommended dilutionsIHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenProtein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesKMT3C; HSKM-B; ZMYND14; N-lysine methyltransferase SMYD2; Histone methyltransferase SMYD2; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2; SMYD2
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolSMYD2
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Short nameAnti-SMYD2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameSMYD2 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameSET and MYND domain containing 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-04-28
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Entrez gene record
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RefSeq identity
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Classification
- SET domain containing
- Lysine methyltransferases
- Zinc fingers MYND-type
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data