Mouse Monoclonal IgG1 Anti-Uroplakin III [AU1]

  • Catalog number
    UP3001-G
  • Price
    Please ask
  • Size
    5 ml
  • Availability
    Please contact us to check the availability
  • Immunogen
    Asymmetric Unit Membrane (AUM) preparation from bovine bladder
  • Specificity
    Uroplakin III membrane protein
  • Species reactivity
    Human, cattle, rat, pig
  • Product presentation
    Protein A purified antibody lyophilized from PBS containing 0.09% NaN3 and 0.5% BSA after reconstitution with 1 ml distilled water
  • Product category
    Primary Antibody
  • Antibody s raised in
    Mouse
  • Antibody s isotype
    IgG1
  • Antibody s clone
    AU1
  • Product is supplied as
    ready to use
  • Recommended concentration for use
    neat
  • Protein concentration
    N/A
  • Positive control
    Urothel
  • Pretreatment
    Pre-treatment of paraffin sections with proteinase K or trypsin
  • Tested applications
    IHC (P), IHC in cryostat sections may require formaldehyde fixation, WB
  • Recommended secondary reagent
    We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC (Art. No. PK-6102) or ABC AP (Art. No. AK-5002) systems are applicable.
  • Storage method
    Store at 2-8°C
  • UniProt number
    Go to UniProt/SwissProt
  • Litterature
    1. Moll R, Wu XR, Lin JH, Sun TT (1995) Uroplakins, specific membrane proteins of urothelial umbrella cells, as histological markers of metastatic trasitional cell carcinomas. Am. J. Pathol. 147; 1383-1397. 2. Romith R, Jezernik K, Maera A (1998) Uroplakins and cytokeratins in the regenerating rat urothelium after sodium saccharin treatment. Histochem Cell Biol 109:263-269. 3. Kaufmann O, Volmering J, and Dietel M. (2000) Uroplakin III is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinoma. Am. J. Clin. Pathol. 113; 683-687. 4. Ramos-Vara JA, Miller MA, Boucher M, Roudabush A, and Johnson GC. (2003) Immunohistochemical detection of uroplakin III, cytokeratin 7, and cytokeratin 20 in canine urothelial tumors. Vet. Pathol. 40(1); 55-62.
  • Tips
    *Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
    Monoclonal   IgG1   Uroplakin   III   [AU1]  
  • Gene symbol
    CPLX3, MGAT3, MGST3, P4HA3, CASP5, IGHVIII-82, THAP4, MT-CSB3, IGHVIII-44, IGHVIII-67-4
  • Short name
    Research
  • Technique
    Mouse monoclonal, anti-, Mouse, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG1
  • Species
    Mouse, Mouses
  • Alternative name
    Uroplakin III
  • Alternative technique
    murine, antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
  • Synonyms gene name
    • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-08-27
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Mannosyl-glycoprotein N-acetylglucosaminyltransferases
  • VEGA ID
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    caspase 5
  • Synonyms gene name
    • caspase 5, apoptosis-related cysteine protease
    • caspase 5, apoptosis-related cysteine peptidase
  • Synonyms
  • Locus
  • Discovery year
    1996-09-13
  • Entrez gene record
    838
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Caspases
    • Caspase recruitment domain containing
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (III)-82 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (III)-82
    • immunoglobulin heavy variable (III)-82 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    mitochondrially encoded conserved sequence block III
  • Synonyms gene
  • Synonyms gene name
    • conserved sequence block III
  • Synonyms
  • Locus
  • Discovery year
    1989-10-11
  • Pubmed identfication
  • Classification
    • Mitochondrially encoded regions
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (III)-44 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (III)-44
    • immunoglobulin heavy variable (III)-44 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (III)-67-4 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (III)-67-4
    • immunoglobulin heavy variable (III)-67-4 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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