Mouse Monoclonal [clone P12/1] (IgG2a) to Human C5AR1 / CD88 / C5a Receptor Antibody

  • Catalog number
    GEN245756
  • Price
    Please ask
  • Size
    50ug
  • Also known as
    C5AR1 / CD88 / C5a Receptor
  • Other names
    C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1; complement component 5a receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    C5AR1
  • Gene name synonims
    N/A
  • Other gene names
    C5AR1; C5AR1; C5A; C5AR; C5R1; CD88; C5AR; C5R1; C5a-R; C5aR
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2a
  • Clone
    P12/1
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes the C5a receptor (C5aR) CD88, which is predominantly expressed on cells of the myeloid lineage. Clone P12/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31). Clone P12/1 does not inhibit the binding of C5a to its receptor. Immunogen: C5aR - peptide: Met1 - Asn31.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Purified
  • Form Appearance
    0.09% sodium azide
  • Concentration
    1 miligram per 1 mililiter
  • Storage and shipping
    Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
  • Tested applications
    Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB), Flow Cytometry (FC/FACS)
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • French translation
    anticorps
  • Gene target
    Monoclonal   P12/1]   IgG2a   C5AR1   CD88   C5a   Receptor  
  • Gene symbol
    C5AR1, POLE4, RPL37P14, H3P5
  • Short name
    Mouse Monoclonal [clone P12/1] (IgG2a) C5AR1 / CD88 / C5a Receptor Antibody
  • Technique
    Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG2a
  • Species
    Human, Humans, Mouses
  • Alternative name
    Anti-Mouse Monoclonal [clone P12/1] (IgG2a) to Human C5AR1 / CD88 / C5a Receptor
  • Alternative technique
    antibodies, murine
  • Alternative to gene target
    complement component 5a receptor 1, C5A and C5AR and C5R1 and CD88, C5AR1 and IDBG-59445 and ENSG00000197405 and 728, C5a anaphylatoxin receptor activity, Cell surfaces, C5ar1 and IDBG-146297 and ENSMUSG00000049130 and 12273, BT.34208 and IDBG-639986 and ENSBTAG00000020872 and 101908388,493645
  • Clone name
    P12
Gene info
  • Identity
  • Gene
  • Long gene name
    complement C5a receptor 1
  • Synonyms gene
  • Synonyms gene name
    • complement component 5 receptor 1 (C5a ligand)
    • complement component 5a receptor 1
  • Synonyms
  • Locus
  • Discovery year
    1991-12-04
  • Entrez gene record
    728
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Complement component GPCRs
    • Complement system regulators and receptors
    • CD molecules
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    DNA polymerase epsilon 4, accessory subunit
  • Synonyms gene name
    • polymerase (DNA-directed), epsilon 4 (p12 subunit)
    • polymerase (DNA) epsilon 4, accessory subunit
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2002-07-08
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • DNA polymerases
  • VEGA ID
Gene info
Gene info
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