Mouse Monoclonal [clone MEM-258] (IgG1) to Human MCP / CD46 Antibody

  • Catalog number
    GEN245913
  • Price
    Please ask
  • Size
    50ug
  • Also known as
    MCP / CD46
  • Other names
    membrane cofactor protein isoform 1; Membrane cofactor protein; membrane cofactor protein; measles virus receptor; complement membrane cofactor protein; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; CD46 antigen, complement regulatory protein; trophoblast-lymphocyte cross-reactive antigen; antigen identified by monoclonal antibody TRA-2-10; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); CD46 molecule, complement regulatory protein; TLX; Trophoblast leukocyte common antigen; CD_antigen: CD46
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    MCP
  • Gene name synonims
    CD46
  • Other gene names
    CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG1
  • Clone
    MEM-258
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Protein A Purified
  • Form Appearance
    PBS, 0.09% sodium azide. Sourced in TCS.
  • Concentration
    1 miligram per 1 mililiter
  • Storage and shipping
    Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
  • Tested applications
    Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    Monoclonal   MEM-258]   IgG1   MCP   CD46  
  • Gene symbol
    CD46, CAPG, CCL8, SLC25A33, CCL7, CCL13, CCR2, CCL2
  • Short name
    Mouse Monoclonal [clone MEM-258] (IgG1) MCP / CD46 Antibody
  • Technique
    Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG1
  • Species
    Human, Humans, Mouses
  • Alternative name
    Anti-Mouse Monoclonal [clone MEM-258] (IgG1) to Human MCP / CD46
  • Alternative technique
    antibodies, murine
  • Alternative to gene target
    CD46 molecule, complement regulatory protein, AHUS2 and MCP and MIC10 and TLX and TRA2.10, CD46 and IDBG-106372 and ENSG00000117335 and 4179, cadherin binding, Cell surfaces, Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221, BT.68611 and IDBG-638462 and ENSBTAG00000005397 and 280851
  • Clone name
    MEM-258
Gene info
  • Identity
  • Gene
  • Long gene name
    CD46 molecule
  • Synonyms gene
  • Synonyms gene name
    • antigen identified by monoclonal antibody TRA-2-10
    • membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
    • CD46 antigen, complement regulatory protein
    • CD46 molecule, complement regulatory protein
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1988-08-31
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Sushi domain containing
    • Complement system regulators and receptors
    • CD molecules
  • VEGA ID
  • Locus Specific Databases
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    C-C motif chemokine ligand 8
  • Synonyms gene
  • Synonyms gene name
    • small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
    • chemokine (C-C motif) ligand 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1996-11-14
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Chemokine ligands
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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