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Also known as
CD40
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Other names
tumor necrosis factor receptor superfamily member 5 isoform 1; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40L receptor; CD40 type II isoform; B cell-associated molecule; B cell surface antigen CD40; CD40 antigen (TNF receptor superfamily member 5); nerve growth factor receptor-related B-lymphocyte activation molecule; CD40 molecule, TNF receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD_antigen: CD40
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CD40
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Gene name synonims
N/A
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Other gene names
CD40; CD40; p50; Bp50; CDW40; TNFRSF5; TNFRSF5
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2a
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Clone
LOB7/6
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Host organism
Mouse (Mus musculus)
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Species reactivity
Dog, Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human CD40 cell surface antigen, a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centers and is vital in T cell-B cell interactions.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Protein A Purified
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Form Appearance
Tris buffered saline, 0.09% sodium azide.
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Concentration
1 miligram per 1 mililiter
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Storage and shipping
Keep the antibody refrigerated at +4 degrees Celsius for short periods of time. For longer periods of time, freeze the antibody and keep it at -20 degrees Celsius. Cycles of freeze/thaw may reduce the activity. Store the antibodies in an undiluted form.
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Tested applications
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
CD40
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Short name
Mouse Monoclonal [clone LOB7/6] (IgG2a) CD40 Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG2a
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Species
Human, Humans, Mouses
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Alternative name
Anti-Mouse Monoclonal [clone LOB7/6] (IgG2a) to Human CD40
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Alternative technique
antibodies, murine
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Alternative to gene target
CD40 molecule, TNF receptor superfamily member 5, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, ubiquitin protein ligase binding, Extracellular, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, BT.42498 and IDBG-643036 and ENSBTAG00000020736 and 286849
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Clone name
LOB7
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