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Also known as
CR2 / CD21
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Other names
complement receptor type 2 isoform 2; Complement receptor type 2; complement receptor type 2; EBV receptor; complement C3d receptor; complement component (3d/Epstein Barr virus) receptor 2; Complement C3d receptor; Epstein-Barr virus receptor; EBV receptor; CD_antigen: CD21
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CR2
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Gene name synonims
CD21
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Other gene names
CR2; CR2; CR; C3DR; CD21; CVID7; SLEB9; C3DR; Cr2; EBV receptor
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
Bu32
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human CD21, a 145kD cell surface glycoprotein expressed by mature B lymphocytes, follicular dendritic cells, subsets of normal thymocytes and subsets of T cells. The CD21 molecule acts as a receptor for complement components C3d, C3dg and iC3b, as well as for Epstein Barr Virus. CD21 is part of the signalling complex that is linked to CD19, CD81 and phosphatidylinositol-3-kinase.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Protein G Purified
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Form Appearance
PBS, pH 7.4, 0.09% sodium azide.
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Concentration
1 miligram per 1 mililiter
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Storage and shipping
Store at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
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Tested applications
Immunohistochemistry (IHC - Paraffin), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
CR2
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Short name
Mouse Monoclonal [clone Bu32] (IgG1) CR2 / CD21 Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1
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Species
Human, Humans, Mouses
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Alternative name
Anti-Mouse Monoclonal [clone Bu32] (IgG1) to Human CR2 / CD21
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Alternative technique
antibodies, murine
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Alternative to gene target
complement component (3d/Epstein Barr virus) receptor 2, C3DR and CD21 and CR and CVID7 and SLEB9, CR2 and IDBG-106349 and ENSG00000117322 and 1380, protein homodimerization activity, Cell surfaces, Cr2 and IDBG-209389 and ENSMUSG00000026616 and 12902, CR2 and IDBG-629275 and ENSBTAG00000038496 and 100335830,407126
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Clone name
Bu32
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