Mouse Monoclonal [clone AT3B2] (IgG2b,k) to Human NCSTN / Nicastrin Antibody

• Catalog number
  GEN245353
• Price
  Please ask
• Size
  0.05 ml

• Also known as
  NCSTN / Nicastrin
• Other names
  nicastrin isoform 1; Nicastrin; nicastrin; anterior pharynx-defective 2; nicastrin; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  NCSTN
• Gene name synonims
  N/A
• Other gene names
  NCSTN; NCSTN; ATAG1874; KIAA0253
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b,k
• Clone
  AT3B2
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  human Nicastrin (34-153aa); Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein G Purified
• Form Appearance
  PBS, pH 7.4, 0.1% sodium azide
• Concentration
  1 miligram per 1 mililiter
• Storage and shipping
  After been aliquoted the antibody should be stored at -20 degrees Celsius. Cycles of freezing and thawing should be avoided as they may damage the polypeptide chains thus reducing the activity of the antibody.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   AT3B2]   IgG2b   NCSTN   Nicastrin  
• Gene symbol
  NCSTN
• Short name
  Mouse Monoclonal [clone AT3B2] (IgG2b k) NCSTN / Nicastrin Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2b
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone AT3B2] (IgG2b,k) to Human NCSTN / Nicastrin
• Alternative technique
  antibodies, murine
• Alternative to gene target
  nicastrin, ATAG1874, NCSTN and IDBG-104034 and ENSG00000162736 and 23385, peptidase activity, Plasma membranes, Ncstn and IDBG-204941 and ENSMUSG00000003458 and 59287, BT.48812 and IDBG-630578 and ENSBTAG00000004334 and 514929
• Clone name
  AT3B2

Gene info

• Identity
  HGNC:17091
• Gene
  NCSTN
• Long gene name
  nicastrin
• Synonyms
  • KIAA0253
  • APH2
• GenBank acession
  • AF240468
• Locus
  1q23.2
• Discovery year
  2005-02-08
• Entrez gene record
  23385
• Pubmed identfication
  • 9039502
  • 10993067
• RefSeq identity
  • NM_015331
• VEGA ID
  OTTHUMG00000033110
• Locus Specific Databases
  • LRG_223

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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