Mouse Monoclonal [clone 73C175.1.1] (IgG1) to Human CHEK2 / CHK2 Antibody

• Catalog number
  GEN245020
• Price
  Please ask
• Size
  50ug

• Also known as
  CHEK2 / CHK2
• Other names
  serine/threonine-protein kinase Chk2 isoform a; Serine/threonine-protein kinase Chk2; serine/threonine-protein kinase Chk2; cds1 homolog; CHK2 checkpoint homolog; checkpoint-like protein CHK2; checkpoint kinase 2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CHEK2
• Gene name synonims
  CHK2
• Other gene names
  CHEK2; CHEK2; CDS1; CHK2; LFS2; RAD53; hCds1; HuCds1; PP1425; CDS1; CHK2; RAD53; Hucds1; hCds1
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  73C175.1.1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  A synthetic peptide obtained from human Chk2 protein sequence was used as immunogen.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein G Purified
• Form Appearance
  PBS, 0.02% sodium azide.
• Concentration
  N/A
• Storage and shipping
  For long term storage keep the antibody at -70C or -80. For shorter storage the antibody can be kept at +4 degrees Celsius. Cycles of freeze/thaw can damage the antibodies and recude their activity, therefore should be avoided as much as possible.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   73C175   IgG1   CHEK2   CHK2  
• Gene symbol
  CHEK2
• Short name
  Mouse Monoclonal [clone 73C175 1 1] (IgG1) CHEK2 / CHK2 Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone 73C175.1.1] (IgG1) to Human CHEK2 / CHK2
• Alternative technique
  antibodies, murine
• Alternative to gene target
  checkpoint kinase 2, CDS1 and CHK2 and hCds1 and HuCds1 and LFS2 and PP1425 and RAD53, CHEK2 and IDBG-3314 and ENSG00000183765 and 11200, transferase activity, nuclei, Chek2 and IDBG-190635 and ENSMUSG00000029521 and 50883, CHEK2 and IDBG-636030 and ENSBTAG00000004956 and 518897
• Clone name
  73C175

Gene info

• Identity
  HGNC:16627
• Gene
  CHEK2
• Long gene name
  checkpoint kinase 2
• Synonyms gene
  • RAD53
• Synonyms gene name
  • CHK2 (checkpoint, S.pombe) homolog
  • CHK2 checkpoint homolog (S. pombe)
• Synonyms
  • CDS1
  • CHK2
  • HuCds1
  • PP1425
  • bA444G7
• GenBank acession
  • AF086904
• Locus
  22q12.1
• Discovery year
  2001-09-19
• Entrez gene record
  11200
• Pubmed identfication
  • 9836640
  • 10097108
• RefSeq identity
  • NM_001005735
• VEGA ID
  OTTHUMG00000151023
• Locus Specific Databases
  • LRG_302

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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