Mouse Monoclonal [clone 5G11] (IgG2a,k) to Human TOPORS Antibody

• Catalog number
  GEN245669
• Price
  Please ask
• Size
  50ug

• Also known as
  TOPORS
• Other names
  E3 ubiquitin-protein ligase Topors isoform 1; E3 ubiquitin-protein ligase Topors; E3 ubiquitin-protein ligase Topors; SUMO1-protein E3 ligase Topors; tumor suppressor p53-binding protein 3; topoisomerase I-binding RING finger protein; topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase; SUMO1-protein E3 ligase Topors; Topoisomerase I-binding RING finger protein; Topoisomerase I-binding arginine/serine-rich protein; Tumor suppressor p53-binding protein 3; p53-binding protein 3; p53BP3
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  TOPORS
• Gene name synonims
  N/A
• Other gene names
  TOPORS; TOPORS; LUN; RP31; P53BP3; TP53BPL; LUN; TP53BPL; p53-binding protein 3; p53BP3
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a,k
• Clone
  5G11
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  N/A; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein A Purified
• Form Appearance
  PBS, pH 7.2
• Concentration
  0.4 mg/ml
• Storage and shipping
  For optimal long term storage, the antibody should be kept at -20 degrees Celsius. We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   5G11]   IgG2a   TOPORS  
• Gene symbol
  TOPORS, SMIM27
• Short name
  Mouse Monoclonal [clone 5G11] (IgG2a k) TOPORS Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2a
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone 5G11] (IgG2a,k) to Human TOPORS
• Alternative technique
  antibodies, murine
• Alternative to gene target
  topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, LUN and P53BP3 and RP31 and TP53BPL, TOPORS and IDBG-55971 and ENSG00000197579 and 10210, metal ion binding, nuclei, Topors and IDBG-136139 and ENSMUSG00000036822 and 106021, TOPORS and IDBG-629770 and ENSBTAG00000005905 and 523321
• Clone name
  5G11

Gene info

• Identity
  HGNC:21653
• Gene
  TOPORS
• Long gene name
  TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
• Synonyms gene
  • RP31
• Synonyms gene name
  • retinitis pigmentosa 31 (autosomal dominant)
  • TOP1 binding arginine/serine rich protein
• Synonyms
  • TP53BPL
  • LUN
• GenBank acession
  • AF098300
• Locus
  9p21.1
• Discovery year
  2003-07-07
• Entrez gene record
  10210
• Pubmed identfication
  • 10352183
  • 12083797
  • 17924349
• RefSeq identity
  • NM_005802
• Classification
  • Ring finger proteins
• VEGA ID
  OTTHUMG00000019743

Gene info

• Identity
  HGNC:31420
• Gene
  SMIM27
• Long gene name
  small integral membrane protein 27
• Synonyms gene
  • C9orf133
  • TOPORS-AS1
• Synonyms gene name
  • chromosome 9 open reading frame 133
  • TOPORS antisense RNA 1 (non-protein coding)
  • TOPORS antisense RNA 1
• Locus
  9p21.1
• Discovery year
  2005-03-22
• Entrez gene record
  100129250
• RefSeq identity
  • NM_001349118
• VEGA ID
  OTTHUMG00000019742

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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