Mouse Monoclonal [clone 4A12-F6] (IgG1,k) to Human CD247 / CD3 Zeta Antibody

• Catalog number
  GEN246545
• Price
  Please ask
• Size
  50ug

• Also known as
  CD247 / CD3 Zeta
• Other names
  T-cell surface glycoprotein CD3 zeta chain isoform 2; T-cell surface glycoprotein CD3 zeta chain; T-cell surface glycoprotein CD3 zeta chain; CD3zeta chain; TCR zeta chain; CD247 antigen, zeta subunit; T-cell receptor T3 zeta chain; CD3Z antigen, zeta polypeptide (TiT3 complex); T-cell antigen receptor complex, zeta subunit of CD3; CD247 molecule; T-cell receptor T3 zeta chain; CD_antigen: CD247
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CD247
• Gene name synonims
  N/A
• Other gene names
  CD247; CD247; T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA; CD3Z; T3Z; TCRZ
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1,k
• Clone
  4A12-F6
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Human CD247; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein A Purified
• Form Appearance
  PBS, pH 7.4.
• Concentration
  0.23 mg/ml
• Storage and shipping
  After aliquoting the antibody should be stored at -20 degrees Celsius. For extended periods of time, storage at -80 degrees Celsius is recommended. Cycles of freezing and thawing may destroy the polypeptide chains of the antibodies and should be avoided.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   4A12-F6]   IgG1   CD247   CD3   Zeta  
• Gene symbol
  CD247
• Short name
  Mouse Monoclonal [clone 4A12-F6] (IgG1 k) CD247 / CD3 Zeta Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone 4A12-F6] (IgG1,k) to Human CD247 / CD3 Zeta
• Alternative technique
  antibodies, murine
• Alternative to gene target
  CD247 molecule, CD3-ZETA and CD3H and CD3Q and CD3Z and IMD25 and T3Z and TCRZ, CD247 and IDBG-104547 and ENSG00000198821 and 919, protein homodimerization activity, Plasma membranes, Cd247 and IDBG-202777 and ENSMUSG00000005763 and 12503, CD247 and IDBG-629556 and ENSBTAG00000012700 and 281056
• Clone name
  4A12-F6

Gene info

• Identity
  HGNC:1677
• Gene
  CD247
• Long gene name
  CD247 molecule
• Synonyms gene
  • CD3Z
• Synonyms gene name
  • CD3z antigen, zeta polypeptide (TiT3 complex)
  • CD247 antigen
• Synonyms
  • CD3H
  • CD3Q
• Synonyms name
  • T-cell surface glycoprotein CD3 zeta chain
• GenBank acession
  • BC025703
• Locus
  1q24.2
• Discovery year
  1989-04-06
• Entrez gene record
  919
• Pubmed identfication
  • 2974162
• RefSeq identity
  • NM_198053
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000034593
• Locus Specific Databases
  • CD247base: Mutation registry for Autosomal recessive CD3Zeta deficiency
  • LRG_36

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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