Mouse Monoclonal [clone 3G4] (IgG2b) to Human ERCC3 / XPB Antibody

  • Catalog number
    GEN245886
  • Price
    Please ask
  • Size
    50ug
  • Also known as
    ERCC3 / XPB
  • Other names
    TFIIH basal transcription factor complex helicase XPB subunit isoform a; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex helicase XPB subunit; BTF2 p89; TFIIH p89; DNA repair helicase; TFIIH 89 kDa subunit; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; basic transcription factor 2 89 kDa subunit; xeroderma pigmentosum, complementation group B; xeroderma pigmentosum group B-complementing protein; TFIIH basal transcription factor complex 89 kDa subunit; excision repair cross-complementing rodent repair deficiency, complementation group 3; excision repair cross-complementation group 3; Basic transcription factor 2 89 kDa subunit; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH 89 kDa subunit; TFIIH p89; Xeroderma pigmentosum group B-complementing protein
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    ERCC3
  • Gene name synonims
    XPB
  • Other gene names
    ERCC3; ERCC3; XPB; BTF2; GTF2H; RAD25; TFIIH; XPB; XPBC; BTF2 p89; TFIIH 89 kDa subunit; TFIIH p89
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG2b
  • Clone
    3G4
  • Host organism
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes an epitope located between aa242-261 of ERCC-3 (largest subunit of TFIIH).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Protein G Purified
  • Form Appearance
    0.1 M Tris-HCl, pH 7.5.
  • Concentration
    1 miligram per 1 mililiter
  • Storage and shipping
    For long term storage, keep the antibody at -20 degrees Celsius. Short term storage of the antibody can be done at +4 degrees Celsius. Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity.
  • Tested applications
    Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    Monoclonal   3G4]   IgG2b   ERCC3   XPB  
  • Gene symbol
    ERCC3
  • Short name
    Mouse Monoclonal [clone 3G4] (IgG2b) ERCC3 / XPB Antibody
  • Technique
    Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG2b
  • Species
    Human, Humans, Mouses
  • Alternative name
    Anti-Mouse Monoclonal [clone 3G4] (IgG2b) to Human ERCC3 / XPB
  • Alternative technique
    antibodies, murine
  • Alternative to gene target
    excision repair cross-complementing rodent repair deficiency, complementation group 3, BTF2 and GTF2H and RAD25 and TFIIH and XPB, ERCC3 and IDBG-68963 and ENSG00000163161 and 2071, protein N-terminus binding, nuclei, Ercc3 and IDBG-133673 and ENSMUSG00000024382 and 13872, ERCC3 and IDBG-639240 and ENSBTAG00000020777 and 507984
  • Clone name
    3G4
Gene info
  • Identity
  • Gene
  • Long gene name
    ERCC excision repair 3, TFIIH core complex helicase subunit
  • Synonyms gene name
    • excision repair cross-complementing rodent repair deficiency, complementation group 3
    • excision repair cross-complementation group 3
  • Synonyms
  • Synonyms name
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • DNA helicases
    • General transcription factor IIH complex subunits
    • Xeroderma pigmentosum complementation groups
    • ERCC excision repair associated
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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