PAX7 (Rhabdomyosarcoma Marker) Mouse Monoclonal Antibody
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Products_type
Antibody
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Products_short_name
[PAX7]
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Products_name_syn
[HUP1; Paired box gene 7; Paired box homeotic gene 7; Paired domain gene HuP1; PAX7 transcriptional factor; PAX7/FKHR fusion gene; PAX7B; RMS2]
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Other_names
[paired box protein Pax-7 isoform 3; Paired box protein Pax-7; paired box protein Pax-7; paired box 7; HuP1]
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Products_gene_name
[PAX7]
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Other_gene_names
[PAX7; PAX7; HUP1; RMS2; PAX7B; HUP1]
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Clonality
Monoclonal
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Clone
[SPM613]
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Reactivity
Human
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Specificity
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stability
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_application
Immunohistochemistry (IHC) Formalin
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Properties
If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
PAX7
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Short name
PAX7 (Rhabdomyosarcoma ) Mouse Monoclonal Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1, kappa
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Species
Mouse, Mouses
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Alternative name
paired box 7 (Rhabdomyosarcoma detection labelled) Mouse monoclonal (antibody to-)
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Alternative technique
antibodies, murine
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Alternative to gene target
paired box 7, HUP1 and PAX7B and RMS2, PAX7 and IDBG-92024 and ENSG00000009709 and 5081, sequence-specific DNA binding, nuclei, Pax7 and IDBG-201015 and ENSMUSG00000028736 and 18509, PAX7 and IDBG-645775 and ENSBTAG00000014967 and 536229
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Gene info
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Identity
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Gene
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Long gene name
paired box 7
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1992-11-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Paired boxes
- PRD class homeoboxes and pseudogenes
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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