Anti-UHRF1 Antibody (1H9-D3-E11)

• Catalog number
  A1319-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  UHRF1
• Target Alternative Name
  E3 ubiquitin-protein ligase UHRF1, Inverted CCAAT box-binding protein of 90 kDa, Nuclear protein 95, Nuclear zinc finger protein Np95, HuNp95, hNp95, RING finger protein 106, FLJ21925, ICBP90, mgC138707, Np95, RNF106, hNP95
• Antibody Type
  Monoclonal
• Clone
  1H9-D3-E11
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human UHRF1 protein fragments expressed in E.coli
• Accession
  Q96T88
• Gene Id
  29128
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
• Purification
  Affinity purified
• Application
  WB
• Positive Control
  WB: Mouse heart, 293T, HeLa nuclear extract and HeLa cell lysates
• Application And Usages
  WB; 1:1000
• Description
  Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication. In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  UHRF1   1H9-D3-E11  
• Gene symbol
  SNRPD3, NCAPD3, TRO, UHRF1
• Short name
  Anti-UHRF1 Antibody (1H9-D3-E11)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG2b
• Alternative name
  Antibody toUHRF1 (antibody to-) (1H9-D3-E11)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11160
• Gene
  SNRPD3
• Long gene name
  small nuclear ribonucleoprotein D3 polypeptide
• Synonyms gene name
  • small nuclear ribonucleoprotein D3 polypeptide (18kD)
  • small nuclear ribonucleoprotein D3 polypeptide 18kDa
• Synonyms
  • SMD3
  • Sm-D3
• GenBank acession
  • U15009
• Locus
  22q11.23
• Discovery year
  1995-04-26
• Entrez gene record
  6634
• Pubmed identfication
  • 1701240
  • 7527560
• RefSeq identity
  • NM_004175
• Classification
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000150727

Gene info

• Identity
  HGNC:28952
• Gene
  NCAPD3
• Long gene name
  non-SMC condensin II complex subunit D3
• Synonyms gene name
  • non-SMC condensin II complex, subunit D3
• Synonyms
  • hCAP-D3
  • CAP-D3
  • hHCP-6
  • KIAA0056
  • FLJ42888
  • hcp-6
• GenBank acession
  • AK124878
• Locus
  11q25
• Discovery year
  2006-09-04
• Entrez gene record
  23310
• Pubmed identfication
  • 7584044
  • 8619474
  • 14532007
• RefSeq identity
  • NM_015261
• Classification
  • Condensin II subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000167172

Gene info

• Identity
  HGNC:12326
• Gene
  TRO
• Long gene name
  trophinin
• Synonyms
  • MAGE-D3
  • KIAA1114
  • MAGED3
• GenBank acession
  • U04811
• Locus
  Xp11.21
• Discovery year
  1997-10-30
• Entrez gene record
  7216
• Pubmed identfication
  • 9533028
  • 11454705
• RefSeq identity
  • NM_016157
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000021640
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:12556
• Gene
  UHRF1
• Long gene name
  ubiquitin like with PHD and ring finger domains 1
• Synonyms
  • ICBP90
  • Np95
  • FLJ21925
  • RNF106
  • TDRD22
• GenBank acession
  • AF129507
• Locus
  19p13.3
• Discovery year
  2000-03-15
• Entrez gene record
  29128
• Pubmed identfication
  • 10646863
  • 28100769
• RefSeq identity
  • NM_001048201
• Classification
  • MicroRNA protein coding host genes
  • Ring finger proteins
  • PHD finger proteins
  • Tudor domain containing
• VEGA ID
  OTTHUMG00000180251

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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