Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11)

Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11) is available 1 time from Biovision labs

A1319-100 | Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11)size: 100 µg | 397.79 USD

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  • Description
    Mouse Monoclonal antibody to detect UHRF1
  • Raised in
    Mouse
  • Clonality
    Monoclonal Antibody (Clone#1H9-D3-E11)
  • Reacts with
    Human
  • Immunogen
    Recombinant human UHRF1 protein fragments expressed in E.coli
  • Target
    UHRF1 (E3 ubiquitin-protein ligase UHRF1, Inverted CCAAT box-binding protein of 90 kDa, Nuclear protein 95, Nuclear zinc finger protein Np95, HuNp95, hNp95, RING finger protein 106, FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95)
  • Research area
    Epigenetics
  • Gene number
    29128
  • Protein number
    Q96T88
  • Physical state
    Colorless liquid
  • Package form
    Affinity purified antibody is supplied in liquid form in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
  • Purity
    Affinity purified
  • Antibody's positive controles
    Western blot: Mouse heart, 293T, HeLa nuclear extract and HeLa cell lysates
  • Approved applications with antibody dilution
    Western blot; 1:1000
  • Scientific context
    Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG domain and recruits DNMT1 methyltransferase to ensure faithful propagation of the DNA methylation patterns through DNA replication. In addition to its role in maintenance of DNA methylation, also plays a key role in chromatin modification: through its tudor-like regions and PHD-type zinc fingers, specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3) and unmethylated at 'Arg-2' (H3R2me0), respectively, and recruits chromatin proteins.
  • Handling and storage
    Before use gently mix the antibody solution. Store this antibody at -20 °C for 12 months. Refer to the label on vial
  • Delivery
    Shipped to your lab under gel pack
  • Precautions
    Manifactured in USA. For Research Use Only! Not to be used in humans
  • Released
    This antibody is available to order since May 2017
  • Additional description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
  • Short name
    Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11)
  • Technique
    Mouse monoclonal, Antibody, Mouse, anti
  • Host
    mouse monoclonal
  • Species
    Mouse
  • Alternative name
    Mouse monoclonal antibody to-UHRF1 (Antibody to) (1H9-D3-E11)
  • Alternative technique
    antibodies
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Mouse Monoclonal Anti-UHRF1 Antibody (1H9-D3-E11)
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