Anti-SMC1A Antibody (4C5-C8-A11)

• Catalog number
  A1337-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  SMC1A
• Target Alternative Name
  Structural maintenance of chromosomes protein 1A, SMC protein 1A, SMC-1-alpha, SMC-1A, Sb1.8, SMC1A
• Antibody Type
  Monoclonal
• Clone
  4C5-C8-A11
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human SMC1A (C-term) protein fragments expressed in E.coli
• Accession
  Q14683
• Gene Id
  8243
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol
• Purification
  Affinity purified
• Application
  WB, IF
• Positive Control
  WB: MOLT-4, U87 mg and Hela NE cell lysates; IF: HeLa cells
• Application And Usages
  WB; 1:1000, IF; 1:100
• Description
  Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SMC1A   4C5-C8-A11  
• Gene symbol
  SNAR-A11, PCDHGA11, SMC1A
• Short name
  Anti-SMC1A Antibody (4C5-C8-A11)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG1
• Alternative name
  Antibody toSMC1A (antibody to-) (4C5-C8-A11)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:34314
• Gene
  SNAR-A11
• Long gene name
  small NF90 (ILF3) associated RNA A11
• Synonyms gene name
  • small nuclear ILF3/NF90-associated RNA A11
  • small ILF3/NF90-associated RNA A11
• Synonyms
  • snaR-A55323591
• GenBank acession
  • EU071061
• Locus
  19q13.33
• Discovery year
  2008-06-20
• Entrez gene record
  100169954
• Pubmed identfication
  • 17855395
• RefSeq identity
  • NR_024225
• Classification
  • Small NF90 (ILF3) associated RNAs

Gene info

• Identity
  HGNC:8698
• Gene
  PCDHGA11
• Long gene name
  protocadherin gamma subfamily A, 11
• Synonyms
  • PCDH-GAMMA-A11
• GenBank acession
  • AF152505
• Locus
  5q31.3
• Discovery year
  2000-06-28
• Entrez gene record
  56105
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018914
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000164055

Gene info

• Identity
  HGNC:11111
• Gene
  SMC1A
• Long gene name
  structural maintenance of chromosomes 1A
• Synonyms gene
  • SMC1L1
• Synonyms gene name
  • SMC1 (structural maintenance of chromosomes 1, yeast)-like 1
  • SMC1 structural maintenance of chromosomes 1-like 1 (yeast)
• Synonyms
  • DXS423E
  • KIAA0178
  • SB1.8
  • Smcb
• GenBank acession
  • S78271
• Locus
  Xp11.22
• Discovery year
  2000-08-11
• Entrez gene record
  8243
• Pubmed identfication
  • 7757074
  • 17273969
• RefSeq identity
  • NM_006306
• Classification
  • Structural maintenance of chromosomes proteins
  • Cohesin complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000021614
• Locus Specific Databases
  • Global Variome shared LOVD
  • LOVD
  • Global Variome shared LOVD
  • LRG_773

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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