Anti-SMARCC1 Antibody (2A4-H7-C12)

• Catalog number
  A1315-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  SMARCC1
• Target Alternative Name
  BRG1-associated factor 155, BAF155, SWI/SNF complex 155 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1
• Antibody Type
  Monoclonal
• Clone
  2A4-H7-C12
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human SMARCC1 protein fragments expressed in E.coli
• Accession
  Q92922
• Gene Id
  6599
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol
• Purification
  Affinity purified
• Application
  WB
• Positive Control
  WB: K562, Jurkat and HeLa cell lysates
• Application And Usages
  WB; 1:1000
• Description
  Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SMARCC1   2A4-H7-C12  
• Gene symbol
  ERVK3-5, SMARCC1, NME7, HHLA2
• Short name
  Anti-SMARCC1 Antibody (2A4-H7-C12)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG1
• Alternative name
  Antibody toSMARCC1 (antibody to-) (2A4-H7-C12)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:39110
• Gene
  ERVK3-5
• Long gene name
  endogenous retrovirus group K3 member 5
• Synonyms gene name
  • endogenous retrovirus group K3, member 5
• Synonyms
  • HML6-c12
• GenBank acession
  • FR714895
• Locus
  12q24.12
• Discovery year
  2011-05-05
• Pubmed identfication
  • 18077721
  • 21542922

Gene info

• Identity
  HGNC:11104
• Gene
  SMARCC1
• Long gene name
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
• Synonyms gene name
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
• Synonyms
  • BAF155
  • SRG3
  • Rsc8
  • CRACC1
• GenBank acession
  • U66615
• Locus
  3p21.31
• Discovery year
  1998-05-15
• Entrez gene record
  6599
• Pubmed identfication
  • 8804307
• Classification
  • PBAF complex
  • BAF complex
  • GBAF complex
  • Small nucleolar RNA protein coding host genes
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000133519

Gene info

• Identity
  HGNC:20461
• Gene
  NME7
• Long gene name
  NME/NM23 family member 7
• Synonyms gene name
  • non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • FLJ37194
  • NM23-H7
  • CFAP67
• Synonyms name
  • cilia and flagella associated protein 67
• GenBank acession
  • AF153191
• Locus
  1q24.2
• Discovery year
  2003-02-24
• Entrez gene record
  29922
• Pubmed identfication
  • 19852809
• RefSeq identity
  • NM_013330
• Classification
  • NME/NM23 family
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000034586

Gene info

• Identity
  HGNC:4905
• Gene
  HHLA2
• Long gene name
  HERV-H LTR-associating 2
• Synonyms
  • B7H7
  • B7-H5
  • B7y
  • B7-H7
• GenBank acession
  • AF126162
• Locus
  3q13.13
• Discovery year
  1999-09-07
• Entrez gene record
  11148
• Pubmed identfication
  • 10444326
  • 23784006
  • 22488247
• RefSeq identity
  • NM_007072
• Classification
  • C1-set domain containing
  • V-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000159224

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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