Anti-PPP1A Antibody (1C11-C10-H5-E9)

  • Catalog number
    A1328-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    PPP1A
  • Target Alternative Name
    Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A
  • Antibody Type
    Monoclonal
  • Clone
    1C11-C10-H5-E9
  • Species Reactivities
    Human
  • Immunogen Sequence
    Recombinant human PPP1A protein expressed in E.coli
  • Accession
    P53095
  • Gene Id
    5499
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
  • Purification
    Affinity purified
  • Application
    WB, IF, IHC
  • Positive Control
    WB: MCF7, K562, Hela, HEPG2 and Jurkat whole cell lysates; IF: HeLa cells; IHC: human bresat cancer tissue
  • Application And Usages
    WB; 1:1000; IF; 1:300; IHC; 1:500- 11000
  • Description
    Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans
  • Handling
    The antibody solution should be gently mixed before use
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Verified
  • Immunofluorescence Verified
    Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Additional description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    C12orf57, NME5, SEPTIN5, PPP1CA, HHLA2, VSIR, FGFR1, SEPTIN4
  • Short name
    Anti-PPP1A Antibody (1C11-C10-H5-E9)
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Isotype
    Mouse IgG1
  • Alternative name
    Antibody toPPP1A (antibody to-) (1C11-C10-H5-E9)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    protein phosphatase 1 catalytic subunit alpha
  • Synonyms gene
  • Synonyms gene name
    • protein phosphatase 1, catalytic subunit, alpha isoform
    • protein phosphatase 1, catalytic subunit, alpha isozyme
  • Synonyms
  • Locus
  • Discovery year
    1989-10-11
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Protein phosphatase catalytic subunits
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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