Anti-KIAA1967 Antibody (3G4-D11-D7)

• Catalog number
  A1336-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Cell cycle and apoptosis regulator protein 2
• Target Alternative Name
  Cell cycle and apoptosis regulator protein 2, Cell division cycle and apoptosis regulator protein 2, DBIRD complex subunit KIAA1967, Deleted in breast cancer gene 1 protein, DBC1, NET35, p30 DBC
• Antibody Type
  Monoclonal
• Clone
  3G4-D11-D7
• Species Reactivities
  Human, Mouse, Rat, Monkey
• Immunogen Sequence
  Recombinant human KIAA1967 protein fragments expressed in E.coli
• Accession
  Q8N163
• Gene Id
  57805
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
• Purification
  Affinity purified
• Application
  WB, IF, IP
• Positive Control
  WB: HeLa, A549, Jurkat, C6, 3T3 and COS7 cell lysates; IF: HeLa cells; IP: HeLa cells
• Application And Usages
  WB; 1:1000, IF; 1:200, IP
• Description
  Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KIAA1967   3G4-D11-D7  
• Gene symbol
  CCAR2
• Short name
  Anti-KIAA1967 Antibody (3G4-D11-D7)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG1
• Alternative name
  Antibody toKIAA1967 (antibody to-) (3G4-D11-D7)
• Alternative technique
  antibodies
• Alternative to gene target
  KIAA1967, KIAA1967 and IDBG-11125 and ENSG00000158941 and 57805, poly(A) RNA binding, nuclei, 2610301G19Rik and IDBG-177884 and ENSMUSG00000033712 and 219158, KIAA1967 and IDBG-634883 and ENSBTAG00000005469 and 507114

Gene info

• Identity
  HGNC:23360
• Gene
  CCAR2
• Long gene name
  cell cycle and apoptosis regulator 2
• Synonyms gene
  • KIAA1967
• Synonyms gene name
  • KIAA1967
• Synonyms
  • DBC-1
  • DBC1
  • NET35
• Synonyms name
  • deleted in breast cancer 1
• GenBank acession
  • AL834351
• Locus
  8p21.3
• Discovery year
  2004-11-08
• Entrez gene record
  57805
• Pubmed identfication
  • 12370419
• RefSeq identity
  • NM_021174
• VEGA ID
  OTTHUMG00000162249

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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