Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) Mouse Monoclonal Antibody
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Catalog numberMBS438105
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PricePlease ask
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Size5x0.1 mg (Without BSA & Azide at 1mg/mL)
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Products_typeAntibody
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Products_short_name[Cytokeratin 10 (KRT10)]
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Products_name_syn[BCIE, BIE, EHK, Keratin Type I Cytoskeletal 10, KRT10]
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Other_names[keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 10; keratin, type I cytoskeletal 10; keratin 10; Cytokeratin-10; CK-10; Keratin-10; K10]
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Products_gene_name[KRT10]
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Other_gene_names[KRT10; KRT10; BIE; EHK; K10; KPP; BCIE; CK10; KPP; CK-10; K10]
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ClonalityMonoclonal
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Clone[LH2]
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ReactivityHuman, Mouse
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SpecificityThis MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
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Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stabilityAntibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_applicationFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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PropertiesIf you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolKRT10-AS1, KRT10
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Short nameCytokeratin 10 (KRT10) (Suprabasal Epithelial ) Mouse Monoclonal Antibody
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG1, kappa
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SpeciesMouse, Mouses
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Alternative nameCytokeratin 10 (KRT10) (Suprabasal Epithelial detection labelled) Mouse monoclonal (antibody to-)
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameKRT10 antisense RNA 1
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Synonyms gene
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Synonyms gene name
- transmembrane protein 99
- transmembrane protein 99 (putative)
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-12-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekeratin 10
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Synonyms gene
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Synonyms gene name
- keratosis palmaris et plantaris
- keratin 10, type I
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-08-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Keratins, type I
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data