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Also known as
CHROMOGRANIN A
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Other names
chromogranin-A preproprotein; Chromogranin-A; chromogranin-A; SP-I; pituitary secretory protein I; parathyroid secretory protein 1; betagranin (N-terminal fragment of chromogranin A); chromogranin A (parathyroid secretory protein 1); Pituitary secretory protein I; SP-ICleaved into the following 13 chains:Vasostatin-1; Alternative name(s):; Vasostatin IVasostatin-2; Alternative name(s):; Vasostatin II
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CHGA; CHGA; CGA; CgA; SP-I
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Gene name synonims
CHGA; CHGA; CGA; CgA; SP-I
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Other gene names
CHGA; CHGA; CGA; CgA; SP-I
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
LK2H10
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
CHROMOGRANIN A This item recognises human Chromogranin A and related chromogranin polypeptides. The antibody stains endocrine derived cells containing secretory storage granules. In staining of tumour cells the intensity of staining is proportional to the number of secretory storage granules present. Small cell carcinoma of the lung, Merkel cell carcinomas and neuroblastomas exhibit weak staining, whilst most other endocrine derived tumours stain strongly. This clone has been reported to be active in western blotting procedures, but this format is not recommended for such applications.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Ready To Use (Purified IgG - liquid)
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Concentration
N/A
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Storage and shipping
Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. DO NOT FREEZE. the antibody should be stored undiluted. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applications
Immunohistology - Paraffin (IHC), Immunohistology - Frozen (IHC)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Test
MBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps