Mouse anti bax (universal)
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Catalog number
A105M
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Price
Please ask
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Size
100 μg
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Category
Primary Antibodies
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Long description
The immunogen for the anti-universal bax was a synthetic peptide corresponding to amino acids 12 to 24 of the human bax sequence. Bax expression is associated with cell death regulation. The ratio of bax to other bcl-2 family members is believed to regulate apoptosis. Clone 6A7 is conformation dependant and will recognize only detergent treated bax protein and not the native form.
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Antibody come from
A synthetic peptide corresponding to amino acids 12 to 24 of the human bax sequence
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Other description
Provided as solution in phosphate buffered saline with 0.08% sodium azide. Protein A/G Chromatography
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Clone
6A7
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Antigen antibody binding interaction
Mouse anti bax (universal) Antibody
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Antibody is raised in
Mouse
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Antibody s reacts with
Human, Mouse, Rat
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Immunoprecipitation
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Antibody s suited for
Applications: Immunoprecipitation 1µg per million cells.
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Storage
-20ºC
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Relevant references
1. Y.T. Hsu et. al. (1997) J. Biol. Chem., 272(21): 13829-13834 _x000B__x000B_2. Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94: 3668-3672 _x000B__x000B_3. Smoot, R.L., et al (2010) Cancer Res., 70, 1960-1969
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Short name
Mouse anti bax (universal)
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Technique
Mouse, anti, antibody to, mouses
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Host
mouse
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Isotype
IgG1
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Label
unlabeled
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Species
Mouse, Mouses
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Alternative name
Mouse antibody to BCL2-associated X protein (universal)
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Alternative technique
murine, antibodies
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Alternative to gene target
BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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