Montelukast sodium, Leukotriene CysLT1 antagonist

  • Catalog number
    SIH-538-250MG
  • Price
    Please ask
  • Size
    250 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    151767-02-1
  • Description
    Leukotriene CysLT1 antagonist
  • Molecular weight
    608,2 g/mol
  • Primary research fields
    Immunology, Innate Immunity, Macrophage
  • Other name
    1-[[[(1R)-1-[3-(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-methyl]-cyclopropaneacetic acid, monosodium salt, Montelukast sodium, Montelukast monosodium salt, MK-0476, MK-476, KS-1087
  • Product category
    Small Molecules
  • Product type
    Antagonist
  • Chemical formula
    C35H35ClNO3S • Na
  • Origin
    Synthetic
  • Purity pourcentage
    >98% (HPLC); NMR (Conforms)
  • Soluble in
    Soluble in DMSO (50 mg/ml), or water (30 mg/ml), or ethanol (60 mg/ml)
  • Physical appearance
    Powder
  • Storage recommendations
    -20ºC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: D2A Very Toxic Material Causing Other Toxic Effects - Reproductive hazard E Corrosive Material - Corrosive to skin Hazard statement(s): H318 Causes serious eye damage. H361fd Suspected of damaging fertility. Suspected of damaging the unborn child. Precautionary statement(s): P280 Wear protective gloves/ eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • PubChem number
    23663996
  • Scientific context
    Montelukast is a cysteinyl leukotriene receptor 1 (CysLT1) antagonist. It blocks pentylenetetrazole-induced seizures, blood brain barrier disruption and leukocyte migration in mice.
  • Release date
    30/Aug/2016
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of Montelukast sodium (SIH-538), a Leukotriene CysLT1 antagonist. CAS #: 151767-02-1. Molecular Formula: C35H35ClNO3S • Na. Molecular Weight: 608.2 g/mol. Chemical structure of Montelukast sodium, a Leukotriene CysLT1 antagonist (SIH-538). CAS # 151767-02-1. Molecular Formula: C35H35ClNO3S • Na.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.25
  • Additional description
    The antagonist receptor ligand binding will be in contrast with agonist activity. stressma produces more antagonist and receptor related products as 1.
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