Mouse Anti-Human TNF-alpha Monoclonal Antibody, Azide Free Clone B-C7

• Catalog number
  MBS335090
• Price
  Please ask
• Size
  5x0.5 mg

• Products_type
  Antibody
• Products_short_name
  [TNF-alpha]
• Products_name_syn
  [TNF-a]
• Other_names
  [TNF-alpha; Tumor necrosis factor; tumor necrosis factor; tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a]
• Products_gene_name
  [TNF-alpha]
• Other_gene_names
  [TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2]
• Clonality
  Monoclonal
• Clone
  [B-C7]
• Reactivity
  Human
• Specificity
  Recognises both natural and recombinant human TNF-a
• Purity
  Ion exchange chromatography
• Form
  Azide free Phosphate-buffered saline. Sterile-filtered through 0.22 mum and treated to remove endotoxins. Carrier and preservative free
• Storage_stability
  Store at +2-8 degree C for 12 months. DO NOT FREEZE.
• Tested_application
  Immunohistochemistry (IHC), ELISA (EIA), ELISpot, Functional Assay
• Description
  The Mouse Anti- TNF-alpha Monoclonal Antibody, Clone B-C7 is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Sodium azide NaN3 is often used to prevent antibody degradation in 0,02% W/V concentrations. MyBioSource supplies azide free antibodies on request. Recently MyBioSource made this Mouse Anti- TNF-alpha Monoclonal Antibody, Clone B-C7 available without azide. It will stick less and is more suitable for ELISA or in vivo studies. However you need to store the @VV@ frozen and ship on dry ice.
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Test
  MyBioSource supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Latin name
  Mus musculus
• Gene
  Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
• French translation
  anticorps

• Gene target
  TNF-alpha   Monoclonal   B-C7  
• Gene symbol
  TNF, TNFRSF1A, TNFRSF1B, C7, LTBR, SNRPB, ORM2, ERAL1, OR1B1, SPIB
• Short name
  Mouse Anti- TNF-alpha Monoclonal Antibody, Clone B-C7
• Technique
  anti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse Antibody toHuman tumor necrosis factor-a monoclonal (antibody to-), Azide Free clonality B-complement component 7
• Alternative technique
  antibodies, murine
• Alternative to gene target
  complement component 7, C7 and IDBG-18519 and ENSG00000112936 and 730, protein binding, Extracellular, C7 and IDBG-259737 and ENSMUSG00000079105 and 109828, BT.69954 and IDBG-629869 and ENSBTAG00000011766 and 507339
• Clone name
  B-C7

Gene info

• Identity
  HGNC:11892
• Gene
  TNF
• Long gene name
  tumor necrosis factor
• Synonyms gene
  • TNFA
• Synonyms gene name
  • tumor necrosis factor (TNF superfamily, member 2)
• Synonyms
  • TNFSF2
  • DIF
  • TNF-alpha
• Synonyms name
  • TNF superfamily, member 2
• GenBank acession
  • X02910
• Locus
  6p21.33
• Discovery year
  1986-01-01
• Entrez gene record
  7124
• Pubmed identfication
  • 2413547
  • 6392892
• Classification
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000031194

Gene info

• Identity
  HGNC:11916
• Gene
  TNFRSF1A
• Long gene name
  TNF receptor superfamily member 1A
• Synonyms gene
  • TNFR1
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1A
• Synonyms
  • TNF-R
  • TNFAR
  • TNFR60
  • TNF-R-I
  • CD120a
  • TNF-R55
• GenBank acession
  • M75866
• Locus
  12p13.31
• Discovery year
  1991-01-15
• Entrez gene record
  7132
• Pubmed identfication
  • 1655358
  • 2158863
• RefSeq identity
  • NM_001065
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000168267
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_193

Gene info

• Identity
  HGNC:11917
• Gene
  TNFRSF1B
• Long gene name
  TNF receptor superfamily member 1B
• Synonyms gene
  • TNFR2
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 1B
• Synonyms
  • TNFBR
  • TNFR80
  • TNF-R75
  • TNF-R-II
  • p75
  • CD120b
• GenBank acession
  • M32315
• Locus
  1p36.22
• Discovery year
  1991-01-15
• Entrez gene record
  7133
• Pubmed identfication
  • 2158863
  • 8702885
• RefSeq identity
  • NM_001066
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000001829

Gene info

• Identity
  HGNC:1346
• Gene
  C7
• Long gene name
  complement C7
• Synonyms gene name
  • complement component 7
• GenBank acession
  • J03507
• Locus
  5p13.1
• Discovery year
  2001-06-22
• Entrez gene record
  730
• Classification
  • Sushi domain containing
  • Complement system activation components
• VEGA ID
  OTTHUMG00000150340
• Locus Specific Databases
  • C7base: Mutation registry for C7 deficiency
  • LRG_30

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

Gene info

• Identity
  HGNC:11153
• Gene
  SNRPB
• Long gene name
  small nuclear ribonucleoprotein polypeptides B and B1
• Synonyms gene
  • SNRPB1
• Synonyms
  • COD
  • SmB/SmB'
  • Sm-B/B'
  • snRNP-B
• Locus
  20p13
• Discovery year
  1988-11-28
• Entrez gene record
  6628
• Pubmed identfication
  • 1376292
• Classification
  • Small nucleolar RNA protein coding host genes
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000031694

Gene info

• Identity
  HGNC:8499
• Gene
  ORM2
• Long gene name
  orosomucoid 2
• Synonyms
  • AGP-B
  • AGP-B'
  • AGP2
• Synonyms name
  • alpha-1-acid glycoprotein, type 2
• Locus
  9q32
• Discovery year
  1991-03-11
• Entrez gene record
  5005
• Pubmed identfication
  • 4711474
  • 2970990
• RefSeq identity
  • NM_000608
• Classification
  • Lipocalins
• VEGA ID
  OTTHUMG00000021014

Gene info

• Identity
  HGNC:3424
• Gene
  ERAL1
• Long gene name
  Era like 12S mitochondrial rRNA chaperone 1
• Synonyms gene name
  • Era (E. coli G-protein homolog)-like 1
  • Era G-protein-like 1 (E. coli)
  • Era-like 12S mitochondrial rRNA chaperone 1
• Synonyms
  • HERA-B
• GenBank acession
  • AF082657
• Locus
  17q11.2
• Discovery year
  1999-11-19
• Entrez gene record
  26284
• Pubmed identfication
  • 10945472
  • 20604745
• VEGA ID
  OTTHUMG00000132675

Gene info

• Identity
  HGNC:8181
• Gene
  OR1B1
• Long gene name
  olfactory receptor family 1 subfamily B member 1
• Synonyms gene name
  • olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
  • olfactory receptor family 1 subfamily B member 1 (gene/pseudogene)
• Synonyms
  • OR9-B
• GenBank acession
  • AC006313
• Locus
  9q33.2
• Discovery year
  1999-12-09
• Entrez gene record
  347169
• RefSeq identity
  • NM_001004450
• Classification
  • Olfactory receptors, family 1
• VEGA ID
  OTTHUMG00000020616

Gene info

• Identity
  HGNC:11242
• Gene
  SPIB
• Long gene name
  Spi-B transcription factor
• Synonyms gene name
  • Spi-B transcription factor (Spi-1/PU.1 related)
• Synonyms
  • SPI-B
• Locus
  19q13.33
• Discovery year
  1994-12-15
• Entrez gene record
  6689
• Pubmed identfication
  • 1406622
• RefSeq identity
  • NM_003121
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000183039

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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