MOUSE Anti-MOUSE NK-1.1 ANTIGEN:RPE Antibody
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Catalog numberGEN214883
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PricePlease ask
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Size25 Tests
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Also known asCD161b/c
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Other namesKiller cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele A; N/A; N/A; CD161 antigen-like family member B; Lymphocyte antigen 55b; Ly-55b; NKR-P1 34; Natural killer cell surface protein NKR-P1B allele SJL/BALB
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameCD161b/c
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Gene name synonimsN/A
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Other gene namesN/A; Klrb1b; N/A; Ly55b; Nkrp1b; Ly-55b; NKR-P1B
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2a
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ClonePK136
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Host organismMouse (Mus musculus)
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Species reactivityMouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityCD161b/c This item (clone PK136) recognises the mouse NK1.1 cell surface antigen, a cell surface glycoprotein encoded by members of the NKR-P1 gene family.In the mouse the NKR-P1 family has three members, NKR-P1A, -B and -C, whilst in the human only one member has been identified. The human protein has received the designation CD161, and the mouse proteins have been referred to as CD161a, -b, -c etc. Although previously thought to recognise only CD161c, recent data has shown that the PK136 antibody may also react with CD161b. CD161c expression itself is strain specific in mice, but recognition of CD161b by PK136 appears to be even more complex, as only some CD161b positive strains are labelled by the antibody. Engagement of CD161c has been reported to have activating function in NK cells, whilst engagement of CD161b is inhibitory.This item is useful for the identification of NK cells in selected strains of mice (positive on C57BL, FVB/N and NZB, but negative on AKR and BALB/c) and is also expressed by rare subsets of T cells and monocytes. The antibody has also been used for in vivo depletion of NK cells and in vitro activation of NK cells.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceRPE (Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised)
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ConcentrationN/A
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Storage and shippingPrior to reconstitution Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Following reconstitution Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. DO NOT FREEZE. the antibody should be stored undiluted. the antibody is photosensitive and should be protected from light. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 12 months from date of reconstitution.
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Tested applicationsFlow Cytometry (FACS)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Antigens are peptides or recombinant or native dependent on the production method.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolRPE, B3GAT1, CD160, NCR2, NCR1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
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Short nameMOUSE Anti-MOUSE NK-1 1 ANTIGEN:RPE Antibody
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TechniqueAntibody, antigen, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antigenes, mouses
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Hostmouse
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Labelrpe
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SpeciesMouse, Mouses
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Alternative nameAnti-MOUSE ANTI MOUSE NK-1.1 ANTIGEN:RPE
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Alternative techniqueantibodies, antigenes, murine
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Gene info
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Identity
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Gene
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Long gene nameribulose-5-phosphate-3-epimerase
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebeta-1,3-glucuronyltransferase 1
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Synonyms gene
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Synonyms gene name
- CD57 antigen
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-01-07
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Entrez gene record
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RefSeq identity
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Classification
- Beta-1,3-glucuronyltransferases
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCD160 molecule
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Synonyms gene name
- CD160 antigen
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-10-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenatural cytotoxicity triggering receptor 2
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Synonyms gene
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Synonyms gene name
- lymphocyte antigen 95 (activating NK-receptor; NK-p44)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-04-09
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- V-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenatural cytotoxicity triggering receptor 1
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Synonyms gene
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Synonyms gene name
- lymphocyte antigen 94 (mouse) homolog (activating NK-receptor; NK-p46)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-04-09
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
