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Category
Antibody
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Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
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Form
Antigen affinity purified
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Conjugation
Unconjugated
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Clone
Polyclonal antibody
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Recognised antigen
MMP7
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Host animal
Rabbit (Oryctolagus cuniculus)
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Clonality
Polyclonal (rabbit origin)
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Species reactivity
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applications
WB, IHC-P, ELISA
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Recommended dilutions
Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,ELISA: 0.1-0.5ug/ml
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Notes
The stated application concentrations are suggested starting amounts. Titration of the MMP7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented use
This MMP7 antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID
4316
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Purity
Antigen affinity
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Description
Matrix metalloproteinase-7, previously called putative metalloproteinase I (PUMP1) or Matrilysin, has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors. The protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids, respectively). Matrix metalloproteinases play a crucial role in tumor invasion and metastasis. MMP7, a member of the matrix metalloproteinase family, is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain. In addition, mRNA is regulated in a specific and distinct manner in normal and malignant tissues. MMP7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas, however, its implication in early invasive colorectal carcinomas has not been determined. It is a mediator of pulmonary fibrosis and a potential therapeutic target.
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Immunogen
Human partial recombinant protein (AA 1-267) was used as the immunogen for this MMP7 antibody.
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Storage
After reconstitution, the MMP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
